1. Anti-infection
  2. HSV
  3. Omaciclovir

Omaciclovir (Synonyms: H2G)

Cat. No.: HY-116174
Handling Instructions

Omaciclovir (H2G) is a potent and selective inhibitor of herpesvirus replication. Omaciclovir is a nucleoside analog with antiviral activity.

For research use only. We do not sell to patients.

Omaciclovir Chemical Structure

Omaciclovir Chemical Structure

CAS No. : 124265-89-0

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Description

Omaciclovir (H2G) is a potent and selective inhibitor of herpesvirus replication. Omaciclovir is a nucleoside analog with antiviral activity[1].

In Vitro

Omaciclovir is a nucleoside analog with in vitro inhibitory activity against varicella-zoster virus (VZV), herpes simplex virus types 1 and 2 (HSV-1 and -2), Epstein-Barr virus, and human herpesvirus 6. Omaciclovir is also efficacious in simian varicella virus-infected monkeys[1].
Omaciclovir shows antiviral activities against different human herpesviruses with EC50s of 0.72 ± 0.1, 0.62 ± 0.2, 0.015 ± 0.004, 0.048 ± 0.023, 0.047 ± 0.004, 0.035 ± 0.022, and 0.016 ± 0.003 μM for MRC-5 VZV-32, MRC-5 Molly, MeWo VZV-32, MeWo Molly, MeWo Emily, MeWo VZ11, and MeWo VZ30, respectively[1].

Molecular Weight

253.26

Formula

C₁₀H₁₅N₅O₃

CAS No.

124265-89-0

SMILES

O=C1NC(N)=NC2=C1N=CN2C[[email protected]](CO)CCO

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

OmaciclovirH2GHSVHerpes simplex virusherpesvirusantiviralvaricella-zostervirusVZVEpstein-BarrInhibitorinhibitorinhibit

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