Fleroxacin-d3
Fleroxacin-d3 (RO 23-6240-d3) is the deuterium labeled Fleroxacin (HY-B0414). Fleroxacin (RO 23-6240) is a broad-spectrum antimicrobial fluoroquinolone.
For research use only. We do not sell to patients.
- Formula: C17H15D3F3N3O3
- Molecular Weight:372.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 79660-72-3
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Molecular Weight 372.36
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Formula C17H15D3F3N3O3
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SMILES
[2H]C([2H])(N1CCN(CC1)C2=C(C3=C(C(C(C(O)=O)=CN3CCF)=O)C=C2F)F)[2H]
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Synonyms
RO 23-6240-d3; AM-833-d3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Weidekamm, E., et al., Single- and multiple-dose pharmacokinetics of fleroxacin, a trifluorinated quinolone, in humans. Antimicrob Agents Chemother, 1987. 31(12): p. 1909-14. [Content Brief]
[2]. MacDonald, K.S., et al., Evaluation of fleroxacin (RO 23-6240) as single-oral-dose therapy of culture-proven chancroid in Nairobi, Kenya. Antimicrob Agents Chemother, 1989. 33(5): p. 612-4. [Content Brief]
[3]. Rubinstein, E., History of quinolones and their side effects. Chemotherapy, 2001. 47 Suppl 3: p. 3-8; discussion 44-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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