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ADC Payloads Related Products (219)
Related Products (219)
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Diacetyl Agrochelin
0 ImagesCat. No.: HY-130996CAS No.: 247115-75-9Diacetyl Agrochelin is an acetyl derivative of Agrochelin, which is produced by the fermentation of a marine Agrobacterium sp. Diacetyl Agrochelin has cytotoxic activity in tumor cell lines.
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Daunorubicin-13C,d3 TFA
0 ImagesCat. No.: HY-13062ASSynonyms: Daunomycin-13C,d3 TFA); RP 13057-13C,d3 TFA; Rubidomycin-13C,d3 TFADaunorubicin-13C,d3 TFA (Daunomycin-13C,d3 TFA) is the deuterium and 13C-labeled Daunorubicin TFA. Daunorubicin (Daunomycin) is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin inhibits DNA and RNA synthesis. Daunorubicin is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin is also an anthracycline antibiotic. Daunorubicin can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor.
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seco-CBI-PBD dimer
0 ImagesCat. No.: HY-171718CAS No.: 550356-40-6seco-CBI-PBD dimer is a CBI-PBD heterodimer and a minor groove DNA crosslinker. seco-CBI-PBD dimer exhibits cytotoxicity against human tumor cells at sub-pM to low nM levels, shows low sensitivity to P-glycoprotein-mediated drug resistance, and can serve as an ADC payload. seco-CBI-PBD dimer can be used in studies of uterine cancer, breast cancer, non-small cell lung cancer, etc.
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10NH2-11F-Camptothecin
0 ImagesCat. No.: HY-156516CAS No.: 2873460-30-910NH2-11F-Camptothecin is a Camptothecin (HY-16560) analogue that serves as an ADC cytotoxin for the synthesis of antibody-drug conjugates (ADCs). 10NH2-11F-Camptothecin can inhibit tumor growth and is used in cancer research.
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Nampt-IN-10
0 ImagesCat. No.: HY-W1117786CAS No.: 2241015-68-7Nampt-IN-10 (Compound 4) is an efficient inhibitor of nicotinamide phosphoribosyltransferase (NAMPT). Nampt-IN-10 exhibits nanomolar-level inhibitory activity against cell lines such as MDA-MB453, NCI-N87, and NCI-H526. Nampt-IN-10 can be used as an ADC payload, and the ADC constructed with it as the core demonstrates significant anti-tumor activity.
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(R)-Methotrexate-d3
0 ImagesCat. No.: HY-14519CSCAS No.: 2470329-38-3(R)-Methotrexate-d3 is the deuterium labeled (R)-Methotrexate.
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TNF-α agonistic 2
0 ImagesCat. No.: HY-178302CAS No.: 2882900-86-7TNF-α agonistic 2 (Compound 009) is a toxic molecule. TNF-α agonistic 2 reduces the thickness of the right ear in mice. TNF-α agonistic 2 can be used as an ADC toxic molecule.
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SGD-1882-Dap-Val
0 ImagesCat. No.: HY-148760CAS No.: 2057431-94-2SGD-1882-Dap-Val is an intermediate compound. SGD-1882-Dap-Val can be used in the synthesis of antibody-drug conjugates (ADCs).
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Eg5-IN-2
0 ImagesCat. No.: HY-157078CAS No.: 1629735-05-2Eg5-IN-2 (Compound Scaffold B (4)) is an Eg5 inhibitor (IC50: < 0.5 nM). Eg5-IN-2 can be used as an ADC payload for synthesis of ADCs.
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Auristatin S
0 ImagesCat. No.: HY-164107CAS No.: 3028453-70-2Auristatin S is a potent Auristatin payload. Auristatin S binds to the vinca-binding site on tubulin, thereby inhibiting microtubule assembly and inducing cell cycle arrest and apoptosis. Auristatin S acts as a cytotoxic component of antibody-drug conjugates (ADCs) and exerts target-specific cytotoxicity against cancer cells. Auristatin S can be used in the research of lymphoma, anaplastic large cell lymphoma and Hodgkin lymphoma.
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Glucocorticoid receptor agonist-6
0 ImagesCat. No.: HY-171081CAS No.: 2117643-80-6Glucocorticoid receptor agonist-6 (Compound A) is a Glucocorticoid receptor (GR) agonist. Glucocorticoid receptor agonist-6 can be used as a cytotoxic payload for synthesis of antibody-drug conjugates (ADCs).
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DMEA-PNU-159682 dichloroacetate
0 ImagesCat. No.: HY-126665ACAS No.: 1799421-49-0DMEA-PNU-159682 (molecule D12) dichloroacetate is an ADC cytotoxin molecule including metabolites of nemorubicin (MMDX) from liver microsomes and a potent ADCs cytotoxin PNU-159682.
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Pan-RAS-IN-9-(R)-2-Hydroxy-3-methylbutanoic acid
0 ImagesCat. No.: HY-186278CAS No.: 3122549-15-6Pan-RAS-IN-9-(R)-2-Hydroxy-3-methylbutanoic acid is a potent payload for ADC (ADC payload) with pan-inhibitory activity against Ras.
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Tubulysin E
0 ImagesCat. No.: HY-N2346CAS No.: 309935-58-8Tubulysin E is a highly cytotoxic anti-microtubule toxin (anti-microtubule toxins) that is synthesized as an ADC cytotoxin (ADC Cytotoxin). Tubulysin E can be isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. Tubulysin E displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the low nanomolar range. Tubulysin E inhibits microtubule/Tubulin polymerization and leads to cell cycle arrest and apoptosis.
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Exatecan analog 38
0 ImagesCat. No.: HY-178315CAS No.: 2766214-00-8Exatecan analog 38 is a camptothecin derivative with potent topoisomerase I inhibitory activity. Exatecan analog 38 can be connected to monoclonal antibodies via linkers to form antibody-drug conjugate (ADC) molecules. Exatecan analog 38 can be used for cancer research.
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Bac5(1-25)
0 ImagesCat. No.: HY-P5748CAS No.: 170917-43-8Bac5(1-25) is an N-terminal fragment of the bovine proline-rich antimicrobial peptide Bac5.
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Ansamitocin P-3 (Standard)
0 ImagesCat. No.: HY-15739RCAS No.: 66584-72-3Synonyms: Antibiotic C 15003P3 (Standard); Maytansinol isobutyrate (Standard)Ansamitocin P-3 (Standard) is the analytical standard of Ansamitocin P-3. This product is intended for research and analytical applications. Ansamitocin P-3 (Antibiotic C 15003P3) is a microtubule inhibitor. Ansamitocin P-3 is a macrocyclic antitumor antibiotic.
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Nampt-IN-13
0 ImagesCat. No.: HY-164759CAS No.: 2592504-89-5Nampt-IN-13 is a NAMPT inhibitor that serves as a payload for the synthesis of ADCs. Nampt-IN-13 is applicable to cancer-related research.
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O-Me Eribulin
0 ImagesCat. No.: HY-159576CAS No.: 2676196-81-7Synonyms: O-Me B1939; O-Me E7389; O-Me ER-086526O-Me Eribulin is a derivative of Eribulin and is an ADC cytotoxin that can be used for ADC synthesis. O-Me Eribulin can inhibit the cell viability of SKBR3, MDA-MB-468, and A549 cells, with IC50 values of 0.2052, 0.1827, and 0.5151 nM, respectively. O-Me Eribulin can be used for tumor research.
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(R)-(4-NH2)-Exatecan
0 ImagesCat. No.: HY-145397ACAS No.: 3123392-57-1Synonyms: (R)-AZ14170132(R)-(4-NH2)-Exatecan is the R enantiomer of (4-NH2)-Exatecan (Compound A). (R)-(4-NH2)-Exatecan, a topoisomerase inhibitor, is a derivative of Exatecan. (R)-(4-NH2)-Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs).
