Antifolate Control
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Methotrexate γ-Methyl Ester
0 ImagesSynonyms: Methotrexate 5-methyl ester; γ-EMTXMethotrexate γ-Methyl Ester (Methotrexate 5-methyl ester) is an impurity of the folate antagonist Methotrexate (HY-14519).
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Antifolate agent 1
0 ImagesCat. No.: HY-175428CAS No.: 518063-75-7Antifolate agent 1 is a 6-substituted pyrrolopyrimidine antifolate with a 1-carbon bridge. Antifolate agent 1 shows no activity against cells expressing FRα and FRβ, and has no GARFTase inhibitory activity. Antifolate agent 1 can be used as a negative control in the development of folate receptor-targeted antifolates.
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(R)-Pralatrexate
0 ImagesCat. No.: HY-117791CAS No.: 1320211-70-8(R)-Pralatrexate is the (R)-enantiomer of Pralatrexate (HY-10446). Pralatrexate is an antifolate and is a potent dihydrofolate reductasean (DHFR) inhibitor.
