2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. Antifolate
  5. Antifolate Control

Antifolate Control

Antifolate Controls (3):

Cat. No. Product Name Effect Purity
  • HY-135101
    Methotrexate γ-Methyl Ester
    		Control 98.30%
    Methotrexate γ-Methyl Ester (Methotrexate 5-methyl ester) is an impurity of the folate antagonist Methotrexate (HY-14519).
  • HY-175428
    Antifolate agent 1
    		Control
    Antifolate agent 1 is a 6-substituted pyrrolopyrimidine antifolate with a 1-carbon bridge. Antifolate agent 1 shows no activity against cells expressing FRα and FRβ, and has no GARFTase inhibitory activity. Antifolate agent 1 can be used as a negative control in the development of folate receptor-targeted antifolates.
  • HY-117791
    (R)-Pralatrexate
    		Control
    (R)-Pralatrexate is the (R)-enantiomer of Pralatrexate (HY-10446). Pralatrexate is an antifolate and is a potent dihydrofolate reductasean (DHFR) inhibitor.