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Lincomycin-13C,d3
0 ImagesCat. No.: HY-117660S1Synonyms: U-10149-13C,d3Lincomycin-13C,d3 (U-10149-13C,d3) is the deuterium and 13C-labeled Lincomycin (HY-117660). Lincomycin (U-10149) is an orally active lincosamide antibiotic. Lincomycin binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice. -
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KPC-2-IN-3
0 ImagesCat. No.: HY-174980KPC-2-IN-3 (Compound 3b) is a KPC-2 inhibitor with IC50 of 0.533 μM and Kiof 0.194 μM. KPC-2-IN-3 has an antimicrobial activity against carbapenem-resistant K. pneumonia K47-25 and reduces bacterial count with a postantibiotic effect in synergy with Meropenem (HY-13678). KPC-2-IN-3 significantly reduces lung bacterial load in a murine pneumonia model. -
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OCA 983
0 ImagesCat. No.: HY-105914CAS No.: 161856-02-6OCA 983 is an orally active tetrahydrofuranyl 1β-methylcarbapenem antibiotic. OCA 983 exhibits potent inhibitory activity against class A and class C β-lactamases. OCA 983 possesses a broad antibacterial spectrum, and can be used in the research of infectious diseases. -
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Antistaphylococcal agent 1
0 ImagesCat. No.: HY-139834CAS No.: 2350182-68-0Antistaphylococcal agent 1 is an antistaphylococcal therapeutic agent. -
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Oxyphenbutazone-13C6
0 ImagesCat. No.: HY-B1355AS1Oxyphenbutazone-13C6 is the 13C6 labeled Oxyphenbutazone (HY-B1355A). Oxyphenbutazone is a phenylbutazone derivative, with anti-inflammatory effect. Oxyphenbutazone is a non-selective COX inhibitor. Oxyphenbutazone is the metabolite of Phenylbutazone (HY-B0230). Oxyphenbutazone selectively kills non-replicating Mycobaterium tuberculosis. -
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Mtb-cyt-bd oxidase-IN-6
0 ImagesCat. No.: HY-151553CAS No.: 1246461-10-8Mtb-cyt-bd oxidase-IN-6 is a potent Mycobacterium tuberculosis (Mtb) cytochrome bd (cyt-bd) oxidase (MtbCyt-bd Oxidase) inhibitor with an IC50 value of 0.35 μM. Mtb-cyt-bd oxidase-IN-6 can effectively inhibit the growth of Mtb (MIC= 4 μM). Mtb-cyt-bd oxidase-IN-6 can be used in the study of tuberculosis. -
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Antibacterial agent 101
0 ImagesCat. No.: HY-146062CAS No.: 2452306-15-7Antibacterial agent 101 (Compd 7f) is an antimicrobial (antibacterial and antifungal) agent, with MIC values between 4 and 32 µg/mL. -
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Ro 20-0657/000
0 ImagesCat. No.: HY-100622CAS No.: 29606-06-2Ro 20-0657/000 is a metabolite of Trimethoprim. Trimethoprim is a dihydrofolate reductase inhibitor, used as an antibacterial agent in human and veterinary medicine. -
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Lefamulin acetate (Standard)
0 ImagesSynonyms: BC-3781 acetate (Standard)Lefamulin (acetate) (Standard) is the analytical standard of Lefamulin (acetate). This product is intended for research and analytical applications. Lefamulin (BC-3781) acetate is an orally active antibiotic. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. Lefamulin acetate has anti-inflammatory activity. Lefamulin acetate can be used in the research of bacterial infections, such as bacterial pneumonia[1]. -
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Cefotiam-13C,15N2
0 ImagesCat. No.: HY-W770956Synonyms: SCE-963-15N2; Cefotiam Dihydrochloride-15N2 -
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Antibacterial agent 252 hydrochloride
0 ImagesCat. No.: HY-168626ACAS No.: 2841472-37-3Antibacterial agent 252 hydrochloride is an amino acid derivative with antibacterial activity. Antibacterial agent 252 hydrochloride enhances the killing of colistin sulfate (HY-A0089) against a variety of gram-negative bacteria by targeting the bacterial membrane. -
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N-Acetyldemethylphosphinothricin tripeptide
0 ImagesCat. No.: HY-180685CAS No.: 845880-13-9N-Acetyldemethylphosphinothricin tripeptide, a peptide antibiotic, is a compound with herbicidal activity. N-Acetyldemethylphosphinothricin tripeptide consists of the unusual amino acid phosphinothricin (PT) and two alanine residues. N-Acetyldemethylphosphinothricin tripeptide penetrates bacterial cells as a prodrug via peptide uptake systems with subsequent release of PT. -
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Pseudomonic acid C (Standard)
0 ImagesCat. No.: HY-133056RCAS No.: 71980-98-8Algestone acetophenide (Standard) is the analytical standard of Algestone acetophenide. This product is intended for research and analytical applications. Algestone acetophenide is a progesterone drug. Algestone acetophenide can be used in combination with estrogen as a long-acting injectable contraceptive. -
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8-Br-GTP
0 ImagesCat. No.: HY-134274CAS No.: 23197-98-0Synonyms: 8-Bromoguanosine-5'-triphosphate8-Br-GTP, a GTP analog, is a competitive FtsZ polymerization and GTPase activity (Ki of 31.8 μM) inhibitor. 8-Br-GTP can be used for nucleic acid modification. -
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ATD-3169
0 ImagesCat. No.: HY-118281CAS No.: 1788105-63-4ATD-3169 is an antibacterial agent. ATD-3169 enhances endogenous ROS, including superoxide radicals, to inhibit Mycobacterium tuberculosis (Mtb). -
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Bz-DL-Arg-βNA hydrochloride
0 ImagesBz-DL-Arg-βNA hydrochloride is a substrate for endopeptidases but is not hydrolyzed by bacterial dipeptidyl peptidase DPP-III. -
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Antimicrobial agent-7
0 ImagesCat. No.: HY-151401Antimicrobial agent-7 (Compound 12) is a potent antimicrobial agent, and shows potent antimicrobial activity with an MIC range of 2-8 μg/mL against Gram-negative and Gram-positive bacteria. Antimicrobial agent-7 shows anti-inflammatory activity against lipopolysaccharide-induced inflammation. -
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Moxifloxacin prodrug-1 TFA
0 ImagesCat. No.: HY-180118Moxifloxacin prodrug-1 TFA (Compound 1e) is a Moxifloxacin (HY-66011A) prodrug and antibacterial agent. Moxifloxacin prodrug-1 TFA exhibits comparable potent activity as Moxifloxacin against E. coli, S. aureus, K. pneumoniae, A. baumannii, and P. aeruginosa. Moxifloxacin prodrug-1 TFA inhibits Mtb. -
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Myxopyronin B
0 ImagesCat. No.: HY-N21879CAS No.: 88192-99-8Myxopyronin B is an α-pyrone natural product derived from Myxococcus fulvus and acts as an inhibitor of the switch region of bacterial RNA polymerase (RNAP) (IC50 = 24 μM). Myxopyronin B binds to the switch region of RNA polymerase, locking the polymerase clamp into a closed conformation and thereby inhibiting transcription initiation. Myxopyronin B exhibits antibacterial activity against Staphylococcus aureus and Clostridioides difficile, inhibits the early synthesis of toxins A and B, and reduces the abundance of proteins in the branched-chain amino acid fermentation pathway. Myxopyronin B is useful for research related to bacterial infections. -
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