1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-P10546
    Polyalanine peptide
    Inhibitor
    Polyalanine peptide (pALA) is an antimicrobial peptide that targets biofilms and Gram-negative bacteria and is non-toxic to mammalian cells. Polyalanine peptide forms an α-helical conformation that effectively permeabilizes Gram-negative bacterial membranes, thereby inducing lethal cell leakage. Polyalanine peptide can be used in anti-infection research.
    Polyalanine peptide
  • HY-153993A
    Pyrocatechol sulfate TEA
    Pyrocatechol sulfate TEA is a dietary phenolic metabolite and uremic toxin. Pyrocatechol sulfate TEA can be derived from diet and gut Bacterial metabolism. Plasma levels of Pyrocatechol sulfate TEA are sensitive to alcohol exposure and withdrawal, and are negatively correlated with anxiety, depression, and craving for alcohol in severe alcohol use disorder. Pyrocatechol sulfate TEA can be used in studies related to chronic kidney disease and severe alcohol use disorder.
    Pyrocatechol sulfate TEA
  • HY-P2206
    Zelkovamycin
    Zelkovamycin is a cyclic peptide antibiotic originally isolated from Streptomyces. It inhibits growth of X. oryzae, P. oryzae, S. aureus, and A. laidlawii in a concentration-dependent manner when used at concentrations ranging from 0.01 to 300 μg/mL.
    Zelkovamycin
  • HY-NP016
    Brucella bacterial protein
    Activator
    Brucella bacterial protein is native protein that purified from Brucella for life science related research.
    Brucella bacterial protein
  • HY-B0147R
    Pefloxacin (Standard)
    Inhibitor
    Pefloxacin (Standard) (Pefloxacinium (Standard)) is the analytical standard of Pefloxacin (HY-B0147). This product is intended for research and analytical applications. Pefloxacin (Pefloxacinium) is a broad spectrum antibiotic. Pefloxacin blocks DNA replication by inhibiting DNA gyrase. Pefloxacin inhibits DNA relaxation catalyzed by topoisomerase I with an IC50 of 45 μg/mL. Pefloxacin exhibits antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis with MIC90s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin has anti-Plasmodium yoelii infection activity. Pefloxacin increase UVA-induced edema and immunesuppression. Pefloxacin can be used for infection studies.
    Pefloxacin (Standard)
  • HY-112240
    Antibacterial agent 104
    Inhibitor
    Antibacterial agent 104 (Compound 7) is a potent antibacterial agent. Antibacterial agent 104 displays excellent antibacterial activity in vitro and good efficacy in vivo against MRSA.
    Antibacterial agent 104
  • HY-N0113BS
    Hordenine-d6 hydrochloride
    Inhibitor
    Hordenine-d6 (Ordenina-d6; Peyocactine-d6) hydrochloride is deuterium-labeled Hordenine (hydrochloride) (HY-N0113B).
    Hordenine-d<sub>6</sub> hydrochloride
  • HY-119132
    RWJ-416457
    Inhibitor
    RWJ-416457 is an orally active antibacterial agent targeting 23S rRNA ribosome. RWJ-416457 is promising for research of Gram-positive bacterial infections.
    RWJ-416457
  • HY-N8097
    Kushenol W
    Inhibitor
    Kushenol W is a prenylated flavonoid that can be isolated from the root of Sophora flavescens. Kushenol W has antimicrobial effect, with a MIC of 10 μg/mL for Staphylococcus aureus.
    Kushenol W
  • HY-143455
    Germination-IN-2
    Inhibitor
    Germination-IN-2 (compound 15) is a potent germination inhibitor with an IC50 of 1.3 µM. Germination-IN-2 shows anti-germination activity with 3% germination rate.
    Germination-IN-2
  • HY-N18780
    Piper longum extract
    Piper longum extract contains a variety of key active ingredients, including piperine, piperidine, and essential oils, which give it anti-inflammatory, antioxidant, antibacterial, and digestive-promoting effects.
    Piper longum extract
  • HY-111321
    Fuscin
    Inhibitor
    Fuscin, a fungal metabolite, CCR5 receptor antagonist with anti-HIV effects. Fuscin is a respiration and oxidative phosphorylation inhibitor, and also a mitochondrial SH-dependent transport-linked functions inhibitor.
    Fuscin
  • HY-130511
    FCE 22250
    FCE 22250 is a 3-azinomethylrifamycin with long-term in vivo persistence and good oral absorption. FCE 22250 shows superior efficacy against a broad antimicrobial spectrum including mycobacteria.
    FCE 22250
  • HY-P5545
    Lynronne-1
    Inhibitor
    Lynronne-1 is an antimicrobial peptide. Lynronne-1 is active against Gram-positive bacterials, including MDR strains (MIC: 8-32 μg/mL for methicillin-resistant MRSA strains). Lynronne-1 reduces the bacterial load in MRSA infected wound murine model. Lynronne-1 is also effective against P. aeruginosa infection.
    Lynronne-1
  • HY-125161
    MT0703
    Inhibitor
    MT0703 is an aminothiazolyl glycyl cephalosporin with a 1,5-dihydroxy-4-pyridone-2-carbonyl group and has good anti-Pseudomonas activity.
    MT0703
  • HY-W753904S
    Pradofloxacin-d4
    Pradofloxacin-d4 is the deuterium labeled Pradofloxacin (HY-W753904). Pradofloxacin, a third-generation fluoroquinolone antibacterial agent. Pradofloxacin can be used for the study of bacterial infections in the dog and cat, such as skin infections.
    Pradofloxacin-d<sub>4</sub>
  • HY-N12287
    Curcapicycloside
    Inhibitor
    Curcapicycloside (Pilosidine), a norlignan glucoside, exhibits antibacterial activity against Escherichia coli.
    Curcapicycloside
  • HY-163615
    Antimicrobial agent-32
    Inhibitor
    Antimicrobial agent-32 (Compound 4g) is an antimicrobial agent that exhibits significant activity against various bacteria, including Staphylococcus aureus, Bacillus subtilis, Bacillus cereus (MIC=1000 µg/mL), Klebsiella pneumonia, and Staphylococcus aureus (MRSA) (MIC=500 µg/mL), as well as Escherichia coli (MIC=250 µg/mL). Additionally, Antimicrobial agent-32 inhibits the proliferation of MCF-7, HCT-116, and HepG-2 cells, demonstrating anticancer activity.
    Antimicrobial agent-32
  • HY-155530
    PEX5-PEX14 PPI-IN-1
    PEX5-PEX14 PPI-IN-1 (Compound 8) is a PEX14-PEX5 PPI inhibitor. PEX5-PEX14 PPI-IN-1 disrupts the PEX5-TbPEX14 PPI with a Ki of 53 μM. PEX5-PEX14 PPI-IN-1 inhibits the bloodstream form of T. b. brucei (EC50: 5 μM).
    PEX5-PEX14 PPI-IN-1
  • HY-N10414
    Primulic acid I
    Inhibitor
    Primulic acid I (Primulasaponin 1) is a plant-derived triterpenoid saponin with one sugar chain (monodesmoid).
    Primulic acid I
Cat. No. Product Name / Synonyms Application Reactivity