1. Anti-infection
  2. Antibiotic
  3. Cefotiam

Cefotiam (Synonyms: SCE-963)

Cat. No.: HY-B0734
Handling Instructions

Cefotiam (SCE-963) is a parenteral second-generation cephalosporin antibiotic. Cefotiam (SCE-963) has broad-spectrum activity against gram-positive and gram-negative bacterias
.Cefotiam (SCE-963) has effective in preventing infection following a wide range of urologic surgeries.

For research use only. We do not sell to patients.

Cefotiam Chemical Structure

Cefotiam Chemical Structure

CAS No. : 61622-34-2

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Description

Cefotiam (SCE-963) is a parenteral second-generation cephalosporin antibiotic. Cefotiam (SCE-963) has broad-spectrum activity against gram-positive and gram-negative bacterias
.Cefotiam (SCE-963) has effective in preventing infection following a wide range of urologic surgeries[1][2][3].

IC50 & Target

MIC: 1.56 μg/mL (bacterial)

In Vitro

Cefotiam (SCE-963) has great antibacterial activity with the MIC value of 1.56 μg/mL against P. mirabilis IFO 3849[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: P. mirabilis IFO 3849
Concentration: 0.78-1.65 ug / mL
Incubation Time: 4-8 h
Result: Showed great antibacterial activity
In Vivo

Cefotiam (SCE-963) (50-200mg/kg; Subcutaneous; twice a day for 5 days) can cure urinary tract infection with P. mirabilis in mice in appropriate doses for a sufficient length of the time[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female CF1/b mice[2]
Dosage: 50-200mg/kg
Administration: Cefotiam (Subcutaneous; twice a day for 5 days).
Result: Treated the experimental urinary tract infections.
Molecular Weight

525.63

Formula

C18H23N9O4S3

CAS No.
SMILES

O=C(C(N12)=C(CSC3=NN=NN3CCN(C)C)CS[[email protected]]2([H])[[email protected]](NC(CC4=CSC(N)=N4)=O)C1=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Cefotiam
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HY-B0734
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