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CCR Related Products (135)
Related Products (135)
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VCH-286
0 ImagesCat. No.: HY-15571ACAS No.: 891824-47-8VCH-286 is a CCR5 inhibitor that exhibits potent in vitro anti-HIV-1 activity when used alone.
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CMPD167
0 ImagesCat. No.: HY-124848CAS No.: 313994-79-5Synonyms: MRK-1
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Anti-CCR5 Antibody (HEK/1/85a/7a)
0 ImagesCat. No.: HY-P991843Anti-CCR5 Antibody (HEK/1/85a/7a) recognizes an epitope on human CCR5. CCR5 is a seven-transmembrane G-protein-coupled receptor (GPCR). Recommend Isotype Controls: Rat IgG2b kappa, Isotype Control (HY-P990682).
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Anti-CCR1 Antibody
0 ImagesCat. No.: HY-P991938
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CCR3 antagonist 2
0 ImagesCat. No.: HY-177312CAS No.: 606128-24-9CCR3 antagonist 2 (example 66) is a CCR3 antagonist that can be used for the study of inflammatory or allergic condition, particularly an inflammatory or obstructive airways disease.
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RAP-103
0 ImagesCat. No.: HY-P11319CAS No.: 1337998-99-8RAP-103 is an orally active CCR antagonist that provides potent synaptic protection by inhibiting and reversing cytoskeletal changes induced by PrPC/NOX signaling. RAP-103 is potentially useful in Alzheimer's disease (AD) research.
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BX-513
0 ImagesCat. No.: HY-110391CAS No.: 193542-65-3Synonyms: VUF 2274BX-513 is a highly potent and selective CCR1 antagonist. BX-513 effectively inhibits the binding of radiolabeled MIP-1α and RANTES to CCR1, with Ki values of 40 nM and 60 nM, respectively. BX-513 suppresses MIP-1α-induced extracellular acidification, MIP-1α- and RANTES-induced intracellular calcium mobilization, as well as MIP-1α- and RANTES-induced migration of peripheral blood mononuclear cells. BX-513 can be used for the research of rheumatoid arthritis and multiple sclerosis.
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ABT-182
0 ImagesCat. No.: HY-P991941ABT-182 is an antibody against human CCR8.
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Maraviroc-d6
0 ImagesCat. No.: HY-13004SCAS No.: 1033699-22-7Maraviroc-d6 (UK-427857-d6) is the deuterium labeled Maraviroc. Maraviroc (UK-427857) is a selective CCR5 antagonist with activity against human HIV.
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Catenarin
0 ImagesCatenarin, an anthraquinone compound, inhibits CCR5- and CXCR4-mediated chemotaxis. Catenarin reduces the phosphorylation of mitogen-activated protein kinases (p38 and JNK) and their upstream kinases (MKK6 and MKK7), and calcium mobilization. Catenarin shows anti-inflammatory effect and suppresses leukocyte migration in the diabetes. Catenarin exhibits significant inhibitory effects against Gram-positive bacteria. Catenarin prevents type 1 diabetes (T1D) in nonobese diabetic mice[1][2].
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cis-J-113863
0 ImagesCat. No.: HY-103360ACAS No.: 202796-41-6Synonyms: UCB35625cis-J-113863 is a competitive chemokine receptor 1 (CCR1) antagonist, with IC50 values of 0.9 and 5.8 nM for human and mouse CCR1 receptors, respectively.
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Histamine glutarimide
0 ImagesSynonyms: XC8Histamine glutarimide (XC8) is an orally active anti-asthma agent. Histamine glutarimide blocks the maturation of chemokines (CCL2, CCL7, CCL8, CCL13) and inhibits the migration of eosinophils and the degranulation of mast cells. In asthma models induced by carrageenan and rat ovalbumin, Histamine glutarimide can reduce airway resistance and the count of eosinophils in bronchoalveolar lavage fluid. Histamine glutarimide can be used in asthma research.
