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CCR Related Products (135)
Related Products (135)
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GSK163929
0 ImagesCat. No.: HY-12944CAS No.: 716354-04-0GSK163929 (compound 122) is an orally active, anti-HIV CCR5 antagonist with low inhibitory potency against hEGR. GSK163929 had no adverse effects in rats at 2000 mg/kg/day (i.v., 7 d) and in dogs at 250 mg/kg/day (i.v., 7 d).
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AZD-1678 (Standard)
0 ImagesCat. No.: HY-109511RCAS No.: 942137-41-9
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mNOX-E36
0 ImagesCat. No.: HY-177933mNOX-E36 is a murine-specific analogue of NOX-E36 (HY-148100), an anti-CCL-2 L-RNA aptamer that binds and neutralises the mouse chemokine CCL-2. mNOX-E36 reduces scarring in an experimental murine model of glaucoma filtration surgery (GFS). mNOX-E36 ameliorates lupus nephritis in mice. mNOX-E36 can be used for GFS and lupus nephritis research.
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BMS-457
0 ImagesCat. No.: HY-111037CAS No.: 946594-19-0BMS-457 is a potent and selective CCR1 antagonist. BMS-457 can be used in the study of rheumatoid arthritis.
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Dicytidine 5′-triphosphate
0 ImagesCat. No.: HY-177596CAS No.: 149297-81-4Synonyms: Cp3CDicytidine 5′-triphosphate (Cp3C) is a cytosine-containing dinucleoside polyphosphate. Dicytidine 5′-triphosphate inhibits the intracellular accumulation of trans-resveratrol and trans-piceid. Dicytidine 5′-triphosphate induces the expression of CCR2 and upregulates the expression of PAL1 and 4CL1.
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AZ760
0 ImagesCat. No.: HY-160658CAS No.: 912461-36-0AZ760 is a CCR8 antagonist. AZ760 shows excellent potency, good lipophilicity and high free fraction in blood. AZ760 exhibits unacceptable hERG inhibition.
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R707
0 ImagesCat. No.: HY-P990653
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C-021 dihydrochloride (Standard)
0 ImagesCat. No.: HY-103364ARCAS No.: 1784252-84-1C-021 (dihydrochloride) (Standard) is the analytical standard of C-021 (dihydrochloride). This product is intended for research and analytical applications. C-021 dihydrochloride is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 dihydrochloride effectively prevents human CCL22-derived [35S]GTPγS from binding to the receptor with an IC50 of 18 nM.
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SB-328437 (Standard)
0 ImagesCat. No.: HY-103363RCAS No.: 247580-43-4SB-328437 (Standard) is the analytical standard of SB-328437 (HY-103363). This product is intended for research and analytical applications. SB-328437 is a potent, selective non-peptide CCR3 antagonist with an IC50 of 4.5 nM. SB-328437 can inhibit eosinophil migration induced by eotaxin, eotaxin-2, and monocyte chemotactic protein-4. In addition, SB-328437 can sensitize 5-FU (HY-90006)-resistant gastric cancer cells. SB-328437 can also reduce the recruitment of neutrophils to the lungs and pulmonary inflammation during acute inflammation. SB-328437 can be used in the research of inflammation-related diseases.
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C-021 (Standard)
0 ImagesCat. No.: HY-103364RCAS No.: 864289-85-0C-021 (Standard) is the analytical standard of C-021. This product is intended for research and analytical applications. C-021 is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 effectively prevents human CCL22-derived [35S]GTPγS from binding to the receptor with an IC50 of 18 nM.
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GW 766994 (Standard)
0 ImagesCat. No.: HY-107051RCAS No.: 408303-43-5Synonyms: GW 994 (Standard)GW 766994 (Standard) (GW 994 (Standard)) is the analytical standard of GW 766994 (HY-107051). This product is intended for research and analytical applications. GW 766994 (GW 994) is an orally active and specific chemoKine receptor-3 (CCR3) antagonist. GW 766994 has the potential for asthma and eosinophilic bronchitis research.
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Ilacirnon (Standard)
0 ImagesCat. No.: HY-101713RCAS No.: 1100318-47-5Synonyms: CCX140 (Standard); CCX140-B (Standard)Ilacirnon (Standard) is the analytical standard of Ilacirnon. This product is intended for research and analytical applications. CCX140 (CCX140-B) is a potent CCR2 antagonist.
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AT008
0 ImagesCat. No.: HY-P991540AT008 is an anti-GPCR monoclonal antibody that blocks the binding of chemokine ligands to its cell surface receptor CCR4. AT008 can be studied in research for certain haematological and solid cancers.
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RP23618
0 ImagesCat. No.: HY-123270CAS No.: 207991-30-8RP23618 is a non peptidic RANTES antagonist with the IC50 of 3 μM. RP23618 inhibit RANTES-induced chemotaxis of THP-1 cells.
