GW 766994 (Standard)
GW 766994 (Standard) (GW 994 (Standard)) is the analytical standard of GW 766994 (HY-107051). This product is intended for research and analytical applications. GW 766994 (GW 994) is an orally active and specific chemoKine receptor-3 (CCR3) antagonist. GW 766994 has the potential for asthma and eosinophilic bronchitis research.
For research use only. We do not sell to patients.
- CAS No.: 408303-43-5
- Formula: C21H24Cl2N4O3
- Molecular Weight:451.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
CCR3[1]
Chemical Information
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CAS No. 408303-43-5
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Molecular Weight 451.35
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Formula C21H24Cl2N4O3
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SMILES
NC(C(C=C1)=CC=C1CNC(NC[C@H](OCC2)CN2CC3=CC(Cl)=C(Cl)C=C3)=O)=O
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Synonyms
GW 994 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Neighbour H, et al. Safety and efficacy of an oral CCR3 antagonist in patients with asthma and eosinophilic bronchitis: a randomized, placebo-controlled clinical trial. Clin Exp Allergy. 2014 Apr;44(4):508-16. [Content Brief]
[2]. Zhu C, et al. Targeting CCR3 to Reduce Amyloid-β Production, Tau Hyperphosphorylation, and Synaptic Loss in a Mouse Model of Alzheimer's Disease. Mol Neurobiol. 2017 Dec;54(10):7964-7978. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GW 766994 (Standard) Related Classifications
HY-107051R Related Classifications
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