DNA Stain
There are several different stains that can be used to visualize and photograph DNA after separation by gel electrophoresis. Molecules of the dye adhere to DNA strands and fluoresce under UV light, showing where the bands are within the gel.
Hoechst stains are part of a family of blue fluorescent dyes used to stain DNA.There are three related Hoechst stains: Hoechst 33258, Hoechst 33342, and Hoechst 34580. The dyes Hoechst 33258 and Hoechst 33342 are the ones most commonly used and they have similar excitation/emission spectra.
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DNA Stain Related Products (91)
Related Products (91)
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EthD-d5 bromide
0 ImagesCat. No.: HY-D0021SCAS No.: 1579939-34-6Synonyms: EtBr-d5; Homidium-d5 bromideEthD-d5 bromide is the deuterium labeled Ethidium bromide. EthD bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.
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Cyanine 3 Tyramide methyl indole
0 ImagesCat. No.: HY-136248APurity: 98.67%Cyanine 3 Tyramide methyl indole is a derivative of Cyanine 3 Tyramide (HY-136248). Cyanine 3 Tyramide is an orange fluorescent dye, and is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids.
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TAMRA alkyne, 6-isomer
0 ImagesCat. No.: HY-151680CAS No.: 1352649-44-5TAMRA alkyne, 6-isomer is a linker of TAMRA.
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MeCY5-NHS ester
0 ImagesCat. No.: HY-135413CAS No.: 937739-58-7Synonyms: Sulfo-Cyanine5 NHS esterMeCY5-NHS estera is a reactive dye. MeCY5-NHS estera can be used for the labeling of proteins and nucleic acids.
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Ethidium monoazide bromide
0 ImagesCat. No.: HY-D1246CAS No.: 58880-05-0Ethidium monoazide bromide is a DNA intercalating fluorescent dye that enters bacteria with damaged membranes. Ethidium monoazide bromide can be covalently linked to DNA by photoactivation. Ethidium monoazide bromide stains only dead cells. Ethidium monoazide (bromide) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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AMCA-6-dUTP
0 ImagesCat. No.: HY-D1706CAS No.: 758665-99-5AMCA-6-dUTP can be used for enzymatic labeling of DNA/cDNA.
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DFHBI-2T (solution)
0 ImagesCat. No.: HY-DY1111CAS No.: 1539318-40-5DFHBI-2T solution is a membrane-permeable, RNA aptamer-activated fluorescent probe (Ex/Em=500 nm/523 nm), with a Kd value of 1300 nM for the RNA aptamer Spinach2. DFHBI-2T solution binds to Spinach2, converting the fluorophore to a fluorescent state, stabilizing its planar structure to facilitate the radiative fluorescence decay pathway, and forming a complex with red-shifted excitation and emission peaks. DFHBI-2T solution can be used for RNA imaging in live cells. It is also applicable to research related to fragile X-associated tremor/ataxia syndrome.
Solvent and concentration: DMSO: 5 mM
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Quinacrine acetate
0 ImagesCat. No.: HY-13735HCAS No.: 78901-94-7Synonyms: Acriquine acetateQuinacrine (Acriquine) acetate is a small molecule modulator of the cGAS-STING-TBK1 signaling pathway, possessing immune stimulatory activity. Quinacrine acetate has been explored for its potential therapeutic applications in enhancing anti-tumor immunity. Quinacrine acetate can improve the effectiveness of cancer immunotherapies by addressing the poor immunogenicity of various tumors. Quinacrine acetate also presents a promising strategy for overcoming the limitations associated with immune checkpoint inhibitors in cancer treatment.
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Hoechst 33342 analog trihydrochloride
0 ImagesCat. No.: HY-15627ACAS No.: 159277-19-7Hoechst 33342 analog trihydrochloride is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution. Storage: Keep away from light.
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DMTr-4'-F-U-CED-TBDMS phosphoramidite
0 ImagesCat. No.: HY-D1409CAS No.: 2283414-90-2Synonyms: DMTr-4'-F-uridine-CED-TBDMS phosphoramiditeDMTr-4'-F-U-CED-TBDMS phosphoramidite (DMTr-4'-F-uridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-F-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure.
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Sulfo-CY5-NHS ester potassium
0 ImagesCat. No.: HY-135413ACAS No.: 2230212-27-6Synonyms: Sulfo-Cyanine5 NHS ester potassiumSulfo-CY5-NHS ester potassium is a reactive dye and can be used for labeling protein nucleic acid.
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Basic Blue 20
0 ImagesCat. No.: HY-W110781CAS No.: 82-94-0Basic Blue 20 is a very convenient red-emitting DNA stains. Basic Blue 20 has relatively narrow excitation and emission spectra, with peaks at 633 and 677 nm, respectively. Basic Blue 20 also has a very high resistance to photobleaching.
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DMTr-4'-Me-U-CED-TBDMS phosphoramidite
0 ImagesCat. No.: HY-D1408CAS No.: 1260508-74-4Synonyms: DMTr-4'-Methyluridine-CED-TBDMS phosphoramiditeDMTr-4'-Me-U-CED-TBDMS phosphoramidite (DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-Me-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure.
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BODi-1
0 ImagesCat. No.: HY-D3404CAS No.: 169454-13-1BODi-1 is a fluorescent modulator targeting dsDNA, which binds to dsDNA via a bis-intercalation mechanism (Ex=465 nm, Em=490 nm). BODi-1 exhibits a fluorescence enhancement effect upon binding to nucleic acids, but its fluorescence intensity, anisotropy and average lifetime decrease at higher dye/DNA ratios. When BODi-1 binds to DNA in liposome complexes, it also shows red-shifted emission spectra, along with reduced quantum yield and average lifetime. BODi-1 does not induce significant DNA conformational changes when the dye/DNA ratio is below 0.01. BODi-1 can be used as a fluorescent probe for the characterization of liposome complexes and FRET studies at this ratio.
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7-tert-Butylfascaplysin
0 ImagesCat. No.: HY-1625687-tert-Butylfascaplysin (7-TB) is a derivative of Fascaplysin (HY-112328), that can be isolated from Fascaplysinopsis sp.. 7-tert-Butylfascaplysin induces replication stress, leads to toxic DNA double-strand breaks and apoptosis-like cell death, and thus exhibits cytotoxicity in cancer cells in nanomolar levels. 7-tert-Butylfascaplysin exhibits DNA intercalating activity with EC50 of 3.2 μM.
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Elliptinium acetate
0 ImagesCat. No.: HY-16189CAS No.: 58337-35-2Synonyms: NSC 264137; CeliptiumElliptinium acetate (NSC 264137) is a DNA intercalating agent that is highly cytotoxic to L1 210 cells and covalently binds to nucleic acids from L1210 cells. Elliptinium acetate can be used in cancer research, particularly in metastatic breast cancer.
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2-Aminopurine dihydrochloride
0 ImagesCat. No.: HY-W012642ACAS No.: 1428126-74-22-Aminopurine dihydrochloride is a fluorescent analog of guanosine. 2-Aminopurine dihydrochloride can be used as a fluorescence probe for nucleic acid structure and dynamics. Incorporating 2-Aminopurine dihydrochloride into DNA quenches its fluorescence.
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EDANS sodium
0 ImagesCat. No.: HY-D1079CAS No.: 100900-07-0EDANS sodium is a potent fluorogenic substrates. EDANS sodium is a donor for FRET-based nucleic acid probes and protease substrates. EDANS sodium is often paired with DABCYL or DABSYL. The optimal absorbance and emission wavelengths of EDANS sodium are λabs = 336 nm and λem = 490 nm respectively.
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Biotin-16-UTP
0 ImagesCat. No.: HY-D1686CAS No.: 186033-13-6Synonyms: Biotin-16-UTP tetralithiumBiotin-16-UTP is an active substrate for RNA polymerase. Biotin-16-UTP can replace UTP in the in vitro transcription reaction for RNA labeling.
