D2 Receptor Ligand
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Brexpiprazole S-oxide-d8
0 ImagesSynonyms: DM-3411 d8Brexpiprazole S-oxide-d8 (DM-3411 D8) is the deuterated-labeled Brexpiprazole S-oxide (HY-133152). Brexpiprazole S-oxide (DM-3411) is a metabolite of Brexpiprazole (HY-15780). Brexpiprazole S-oxide is a dopamine D2 receptor ligand that binds to the human dopamine D2L receptor with a Ki of 5.01 nM. Brexpiprazole S-oxide can be used for research on schizophrenia.
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Brexpiprazole S-oxide
0 ImagesCat. No.: HY-133152CAS No.: 1191900-51-2Synonyms: DM-3411Brexpiprazole S-oxide (DM-3411) is a metabolite of Brexpiprazole (HY-15780). Brexpiprazole S-oxide is a dopamine D2 receptor ligand that binds to the human dopamine D2L receptor with a Ki of 5.01 nM. Brexpiprazole S-oxide can be used for research on schizophrenia.
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Fluoroclebopride
0 ImagesFluoroclebopride is a Dopamine receptor ligand with a binding Ki of 0.95 nM for the dopamine D2 receptor and a binding Ki of 5.46 nM for the dopamine D3 receptor. When radiolabeled with 18F, Fluoroclebopride can be used to detect the availability of dopamine D2 and D3 receptors in the caudate nucleus and putamen of primates.
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UCSF34
0 ImagesCat. No.: HY-112320CAS No.: 14862-80-7UCSF34 (Compound 54) is a Haloperidol (HY-14538) analogue. UCSF34 binds to the human D2L receptor, with an estimated pKi of 7.49. UCSF34 can be used in the research of schizophrenia.
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DR/5-HT7AR Ligand-1
0 ImagesCat. No.: HY-187538DR/5-HT7AR Ligand-1 is a ligand with a Ki value of 1.24 nM against human D2R, 5.78 nM against human D3R, 0.67 nM against human 5-HT1AR, and 19.9 nM against human 5-HT7AR. DR/5-HT7AR Ligand-1 can be used for the research of schizophrenia.
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Piquindone
0 ImagesCat. No.: HY-105903CAS No.: 78541-97-6Synonyms: Ro 22-1319Piquindone (Ro 22-1319) is a potent antipsychotic agent. Piquindone binds to a D2 dopaminergic receptor subtype in a sodium-dependent manner. Piquindone can be used in the research of schizophrenia.
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Cinuperone
0 ImagesCat. No.: HY-W754019CAS No.: 82117-51-9Cinuperone is a multi-target competitive receptor ligand and σ receptor antagonist that acts on Dopamine D1, σ, Dopamine D1, and 5-HT2 receptors. Cinuperone shows significantly higher affinity for σ receptors than for Dopamine D1 receptors, and only exhibits moderate binding activity for dopamine D2 receptors. Cinuperone can be used in the research of central nervous system diseases.
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Spectramide
0 ImagesCat. No.: HY-183927CAS No.: 125141-02-8Spectramide is a blood-brain barrier-permeable, reversible, and selective dopamine D2 receptor ligand. Spectramide shows no strong interactions with dopamine D1 receptors, dopamine uptake sites, adrenergic receptor systems, cholinergic receptor systems, or 5-HTR systems. Spectramide can be labeled with 11C or 123I isotopes for use in PET or SPECT. Spectramide preferentially accumulates in the striatum with low uptake in other brain regions, and its accumulation can be blocked by pre-administration of Haloperidol (HY-14538).
