Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4786)
Related Products (4786)
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K-13
0 ImagesCat. No.: HY-120286CAS No.: 108890-90-0K-13 is a cyclic peptide compound synthesized by a specific organozinc reagent. Its synthesis process involves intermolecular and intramolecular Negishi cross-coupling reactions and is one of the shortest routes reported for the synthesis of such cyclic peptides.
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Camphorsulfonate sodium
0 ImagesCat. No.: HY-W272811CAS No.: 34850-66-3Camphorsulfonate sodium is an organic synthesis intermediate. Camphorsulfonate sodium can be used for synthesis of derivatives with SDH inhibitory activity through scaffold hopping. Camphorsulfonate sodium is also an organocatalyst that can be used as a pore-forming additive for modulating the porosity of the graphene film. Camphorsulfonate sodium can be used for binder-free porous graphene film and fungicide research.
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cis-2-Butene-1,4-diol
0 ImagesCat. No.: HY-W027631CAS No.: 6117-80-2cis-2-Butene-1,4-diol serves as a probe for investigating isomerization and hydrogenation/hydrogenolysis reactions. cis-2-Butene-1,4-diol is also a compound used in the synthesis of the antiviral agent Oxetanocin A. cis-2-Butene-1,4-diol undergoes hydrogenation and hydrogenolysis reactions over supported platinum catalysts, with negligible levels of isomerization.
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GL67
0 ImagesCat. No.: HY-149037CAS No.: 179075-30-0Synonyms: N4-Spermine cholesteryl carbamateGL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid that serves as a non-viral siRNA delivery vector and a non-viral gene transfer vector. GL67 enhances the encapsulation efficiency of siRNA in liposomal formulations and promotes the cellular uptake of siRNA across cancer cell membranes. GL67 mediates the transduction of plasmid DNA into cells. GL67 can be used in drug delivery-related research.
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Glycitein-7-O-methyl ether
0 ImagesCat. No.: HY-W783413CAS No.: 75199-40-5Synonyms: 6-MethoxyisoformononetinGlycitein-7-O-methyl ether (6-Methoxyisoformononetin) is an isoflavone antioxidant with a IC50 of 730.53 µg/mL. Glycitein-7-O-methyl ether exhibits weak free radical scavenging activity and shows no antibacterial activity against tested bacteria and fungi. Glycitein-7-O-methyl ether can be used in antioxidant-related research.
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L-Lactic acid calcium hydrate
0 ImagesL-Lactic acid calcium hydrate is the calcium salt of L-Lactic acid. L-Lactic acid calcium hydrate is a building block that can be used as a precursor for the production of bioplastic polymer polylactic acid.
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2'-Hydroxyacetophenone-d7
0 ImagesCat. No.: HY-W739751CAS No.: 1189865-36-8Synonyms: o-Hydroxyacetophenone-d7; o-Acetylphenol-d72'-Hydroxyacetophenone-d7 (o-Hydroxyacetophenone-d7; o-Acetylphenol-d7) is the deuterium labeled 2'-Hydroxyacetophenone (HY-Y1426). 2'-Hydroxyacetophenone is found in alcoholic beverages. 2'-Hydroxyacetophenone is present in tomato, cassia, fried beef, rum, whiskey, cocoa, coffee and black tea. 2'-Hydroxyacetophenone is a flavouring ingredient. Building block in chemical synthesis.
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Isonicotinic acid (Standard)
0 ImagesIsonicotinic acid (Standard) is the analytical standard of Isonicotinic acid (HY-I0736). This product is intended for research and analytical applications. Isonicotinic acid is a pyridine carboxylic acid compound and also a metabolite of Isoniazid (HY-B0329). Derivatives of Isonicotinic acid exhibit antiviral activity against influenza viruses.
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INF7TAT
0 ImagesCat. No.: HY-P11000INF7TAT is an amphipathic cell-penetrating peptide that mediates intracellular delivery of CRISPR ribonucleoproteins. INF7TAT achieves endosomal escape via the INF7 fragment and cell binding via the TAT fragment. It enables intracellular delivery into primary human T cells and hematopoietic stem and progenitor cells, facilitating gene knockout and AAV-mediated homology-directed repair. INF7TAT can be used for genome editing-related research.
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Methoxycarbonyl isocyanate
0 ImagesCat. No.: HY-W178414CAS No.: 5843-42-5Methoxycarbonyl isocyanate can be used for compound synthesis.
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Hydrosorbaldehyde
0 ImagesCat. No.: HY-W747972CAS No.: 4440-65-7Hydrosorbaldehyde is a green leaf volatile and also the main contributor to the fresh, grassy aroma of tea leaves. Hydrosorbaldehyde undergoes irreversible conversion to (E)-2-hexenal via (Z)-3:(E)-2-hexenal isomerase (CsHI). Hydrosorbaldehyde plays a key role in protecting plants against biotic stresses (such as pathogens and insects) and acting as a signaling chemical.
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Antimicrobial peptide BP100 TFA
0 ImagesCat. No.: HY-P12210AAntimicrobial peptide BP100 TFA is a linear undecapeptide with an amphipathic α-helical structure that exhibits antibacterial activity. Antimicrobial peptide BP100 TFA shows in vitro antibacterial activity against a variety of plant and human pathogens. Antimicrobial peptide BP100 TFA binds to and inserts into bacterial cell membranes through electrostatic attraction, triggering membrane permeabilization and ultimately leading to membrane disruption. Antimicrobial peptide BP100 TFA can be used for research on bacterial infections.
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Guaietolin
0 ImagesCat. No.: HY-W412326CAS No.: 63834-83-3Synonyms: Guaietolin (INN); Guethral; GuethuralGuaietolin is an organic synthesis intermediate. Guaietolin is a marker of hypertension with significant reduced level in plasma metabolites. Guaietolin can be used for synthesis of sulfonamide esters with carbonic anhydrase inhibitory activity. Guaietolin can be used for glaucoma and hypertension research.
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3-(5-Phenyl-1,2,4-oxadiazol-3-yl)pyridine
0 ImagesCat. No.: HY-187146CAS No.: 330656-02-53-(5-Phenyl-1,2,4-oxadiazol-3-yl) pyridine is an intermediate. 3-(5-Phenyl-1,2,4-oxadiazol-3-yl) pyridine can be used for the synthesis of positive allosteric modulators of the (α4)3 (β2)2 nicotinic acetylcholine receptor.
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1-Methylimidazole-d3-1
0 ImagesCat. No.: HY-59137S2CAS No.: 4166-68-11-Methylimidazole-d3-1 is the deuterium labeled 1-Methylimidazole. 1-Methylimidazole acts as a membrane performance regulator that promotes the formation of reverse osmosis membranes with a dense ultra-thin polyamide layer. Such membranes exhibit higher flux and salt rejection rate, while also conferring excellent pH stability to the membrane. 1-Methylimidazole can serve as a ligand for ruthenium (II) complexes to construct metal-based anticancer agents.
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2-Fluoro-4-desfluoro bicalutamide
0 ImagesCat. No.: HY-W102331CAS No.: 1159977-36-2Synonyms: BCT-2F2-Fluoro-4-desfluoro bicalutamide (BCT-2F) is a chiral impurity of Bicalutamide (HY-14249).
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ProX1-(SS)-DOTAGA
0 ImagesCat. No.: HY-185120ACAS No.: 3084147-67-8ProX1-(SS)-DOTAGA (Compound 12b) is the unbound portion of the radionuclide in the compound and can be used for targeted delivery to diseases characterized by ACP3 expression.
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H-Arg-Ser-Arg-OH
0 ImagesCat. No.: HY-134578CAS No.: 115035-42-2H-Arg-Ser-Arg-OH is a short peptide. H-Arg-Ser-Arg-OH is a motif of di-leucine and RSRR, it can be used to design larger peptides and compound.
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Antitumor agent-90
0 ImagesCat. No.: HY-153051CAS No.: 131268-74-1Antitumor agent-90 (Compound 17) has cytotoxicity against PC 14 cell and MKN 45 cell. Antitumor agent-90 can be used for cancer research.
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Fosamprenavir sodium
0 ImagesCat. No.: HY-78726ACAS No.: 226700-80-7Synonyms: Amprenavir phosphate sodium; GW 433908 sodiumFosamprenavir sodium is an orally active inhibitor targeting HIV-1 protease and is a prodrug of Amprenavir (HY-17430). Fosamprenavir sodium is hydrolyzed into Amprenavir (VX-478) by cell phosphatases in the intestinal epithelium. Amprenavir binds to the active site of HIV-1 protease, preventing the processing of viral gag and gag-pol polyprotein precursors, thereby inhibiting the formation of mature infectious virus particles and exerting anti-HIV-1 infection activity. Fosamprenavir sodium can be used for the study of human immunodeficiency virus (HIV-1) infection.
