HBV
Hepatitis B virus
HBV (Hepatitis B virus), abbreviated HBV, is a species of the genus Orthohepadnavirus, which is likewise a part of the Hepadnaviridae family of viruses. HBV causes the disease hepatitis B. The hepatitis B virus is classified as the type species of the Orthohepadnavirus, which contains three other species: the Ground squirrel hepatitis virus, Woodchuck hepatitis virus, and theWoolly monkey hepatitis B virus. The genus is classified as part of the Hepadnaviridae family. HBV is divided into four major serotypes (adr, adw, ayr, ayw) based on antigenic epitopes present on its envelope proteins, and into eight genotypes (A–H) according to overall nucleotide sequence variation of the genome. The genotypes have a distinct geographical distribution and are used in tracing the evolution and transmission of the virus. Differences between genotypes affect the disease severity, course and likelihood of complications, and response to treatment and possibly vaccination.
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HBV Related Products (384)
Related Products (384)
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Antibodies (2)
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Cleruvirsen
0 ImagesCat. No.: HY-185923CAS No.: 3072046-94-4Cleruvirsen is a hepatitis B virus surface antigen (HBsAg) inhibitor with anti-hepatitis B virus (HBV) activity. Cleruvirsen can be used for hepatitis B-related research[1].
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Bifendate (Standard)
0 ImagesSynonyms: DDB (Standard)Bifendate (DDB), extracted from Schisandrae chinensis, is an orally active anti-HBV agent against chronic hepatitis B. Bifendate inhibits ATG5-dependent autophagy and attenuates oleic acid-induced lipid accumulation with anti-oxidant properties in vitro. Bifendate can decrease alanine transaminase (ALT) level in mice. Bifendate attenuates hepatic steatosis in cholesterol/bile salt- and high-fat diet-induced hypercholesterolemia in mice. Bifendate potently increases the activity of cytochrome proteins (CYPs) and reverse P-gp-mediated multi-drug resistance (MDR).
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Cetylpyridinium chloride (Standard)
0 ImagesCetylpyridinium (chloride) (Standard) is the analytical standard of Cetylpyridinium (chloride). This product is intended for research and analytical applications. Cetylpyridinium chloride, a cationic quaternary ammonium compound, is an anti-bacterial agent with broad-spectrum activity. Cetylpyridinium chloride is an effective anti-HBV capsid assembly inhibitor with an IC50 of 2.5 μM. Cetylpyridinium chloride is used in pesticides and various types of mouthwashes, and other personal care products.
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Rubiadin (Standard)
0 ImagesRubiadin (Standard) is the analytical standard of Rubiadin (HY-N0444). This product is intended for research and analytical applications. Rubiadin is an orally active free radical scavenger that inhibits the activation of the NF-κB pathway. Rubiadin inhibits osteoclast formation, bone resorption, lipid peroxidation, HBV DNA replication and cancer cell proliferation; reduces pro-inflammatory cytokine levels; induces cancer cell apoptosis; and possesses antifungal, antimalarial, antibacterial and anticonvulsant activities. Rubiadin can be used in the research of osteoporosis, acute inflammation, chronic inflammation, carbon tetrachloride-induced liver injury, Alzheimer's disease, breast cancer, iron overload disorders, hepatitis B virus infection, colon cancer, liver cancer, T-lymphocytic leukemia, cervical cancer, diabetic nephropathy, epileptic seizures, fungal infections, malaria and bacterial infections.
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Tenofovir Disoproxil (Standard)
0 ImagesSynonyms: Bis(POC)-PMPA (Standard); GS 4331 (Standard)Tenofovir Disoproxil (Standard) is the analytical standard of Tenofovir Disoproxil. This product is intended for research and analytical applications. Tenofovir Disoproxil (Bis(POC)-PMPA) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
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Destruxin B2
0 ImagesCat. No.: HY-P2783CAS No.: 79386-00-8Destruxin B2 (compound 5) is a natural depsipeptide that can be inhibits hepatitis B surface antigen (HBsAg) secretion in Hep3B cells with an IC50 1.30 μM.
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Bersacapavir (Standard)
0 ImagesCat. No.: HY-109168RCAS No.: 1638266-40-6Synonyms: JNJ-6379 (Standard); JNJ-56136379 (Standard)Bersacapavir (Standard) is the analytical standard of Bersacapavir (HY-109168). This product is intended for research and analytical applications. Bersacapavir is an HBV capsid assembly modulator. Bersacapavir exerts a dual mechanism of action against both early and late stages of HBV infection by forming complete genome-free empty capsids and inhibiting de novo synthesis of cccDNA. Bersacapavir inhibits HBV replication. Bersacapavir can be used in the research of hepatitis B.
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Periglaucine A
0 ImagesCat. No.: HY-N3094CAS No.: 1025023-04-4Periglaucine A, a hasubanane-type alkaloid, can be isolated from Pericampylus glaucus. Periglaucine A can inhibits HBV surface antigen (HBsAg) secretion in Hep G2.2.15 cells. Periglaucine A also shows anti-HIV-1 activity in C8166 cells (EC50: 204 μM).
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Taribavirin hydrochloride (Standard)
0 ImagesTaribavirin hydrochloride (Standard) is the analytical standard of Taribavirin hydrochloride (HY-10545A). This product is intended for research and analytical applications. Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin hydrochloride is a Ribavirin proagent, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia.
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Isothiafludine (Standard)
0 ImagesCat. No.: HY-111003RCAS No.: 960527-22-4Synonyms: NZ-4 (Standard)Isothiafludine (Standard) is the analytical standard of Isothiafludine (HY-111003). This product is intended for research and analytical applications. Isothiafludine is an orally active non-nucleosidic anti-HBV compound. Isothiafludine inhibits hepatitis B virus replication by blocKing pregenomic RNA encapsidation.
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YZ51
0 ImagesCat. No.: HY-119702CAS No.: 1835652-66-8YZ51 is a derivative of Osalmid (HY-B2116) with stronger ribonucleotide reductase (RR) inhibitory activity and HBV replication inhibition ability than Osalmid. The IC50 of YZ51 against recombinant RR activity is 0.6 μM, and the IC50 against HepG2.2.15 cell RR activity is 23.7 μM.
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Schinlignan B
0 ImagesCat. No.: HY-N15262CAS No.: 77881-08-4Synonyms: Angeloylgomisin PSchinlignan B (Angeloylgomisin P) is a lignan with antioxidant, anti-HIV, anti-HBV activities, which is found in plants of the Schisandra genus. Schinlignan B is promising for research of antioxidant-associated diseases.
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Acutumidine
0 ImagesAcutumidine is a chlorinated alkaloid present in the cultured roots of Menispermum dauricum and Hypserpa nitida Miers. Acutumidine exhibits anti-HBV activity, with an IC50 value of 2.023 mM against hepatitis B virus surface antigen. Acutumidine can be used in studies related to hepatitis B.
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ZINC20451377
0 ImagesCat. No.: HY-171181CAS No.: 2306303-35-3
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7-Deazaneplanocin A
0 ImagesCat. No.: HY-188061CAS No.: 101843-93-07-Deazaneplanocin A is a carbocyclic nucleoside analog with anti-HCV activity and anti-HBV activity (EC50 0.60 µM). 7-Deazaneplanocin A exhibits activity against vaccinia virus and variola virus in vitro, with low cytotoxicity. 7-Deazaneplanocin A is applicable to studies related to viral infections.
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Punicalin (Standard)
0 ImagesCat. No.: HY-N0639RCAS No.: 65995-64-4Punicalin (Standard) is the analytical standard of Punicalin. This product is intended for research and analytical applications. Punicalin is a species that can be isolated from the leaves of Punica granatum. Punicalin is an active molecule against hepatitis b virus (HBV). Punicalin can induce pyroptosis. Punicalin is a Carbonic anhydrase inhibitor. Punicalin blocks the binding of S-glycoprotein and ACE2 receptors. Pnuicalin has anti-inflammatory, antioxidant and antiviral activity.
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HBV-IN-10
0 ImagesCat. No.: HY-145053CAS No.: 2716907-16-1HBV-IN-10 is an enantiomer of compound 6 (WO2021204258A1). Compound 6 is a hepatitis B surface antigen (HBsAg) inhibitor (0.001 μM< EC50 ≤0.05 μM). From patent WO2021204258A1, compound 6.
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Telbivudine (Standard)
0 ImagesSynonyms: Epavudine (Standard); L-Thymidine (Standard); NV 02B (Standard)
