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Cat. No.: HY-N15262

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Schinlignan B

(Synonyms: Angeloylgomisin P)

Schinlignan B (Angeloylgomisin P) is a lignan with antioxidant, anti-HIV, anti-HBV activities, which is found in plants of the Schisandra genus. Schinlignan B is promising for research of antioxidant-associated diseases.

For research use only. We do not sell to patients.

CAS No.: 77881-08-4
Formula: C₂₈H₃₄O₉
Molecular Weight:514.56

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (278 KB)

Schinlignan B Chemical Structure

CAS No.: 77881-08-4

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Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All HIV Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	55.1 μM Compound: Gomisin B	Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay	[PMID: 28818768]
DU-145	IC₅₀	64.7 μM Compound: Gomisin B	Cytotoxicity against human DU145 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay Cytotoxicity against human DU145 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay	[PMID: 28818768]
HEK293	IC₅₀	52 μM Compound: Gomisin B	Cytotoxicity against HEK293 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay Cytotoxicity against HEK293 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay	[PMID: 28818768]
IMR-32	IC₅₀	66.8 μM Compound: Gomisin B	Cytotoxicity against human IMR32 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay Cytotoxicity against human IMR32 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay	[PMID: 28818768]
MDA-MB-231	IC₅₀	60.5 μM Compound: Gomisin B	Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay	[PMID: 28818768]
PANC-1	IC₅₀	53.6 μM Compound: Gomisin B	Cytotoxicity against human PANC1 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay Cytotoxicity against human PANC1 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay	[PMID: 28818768]
SiHa	IC₅₀	51.2 μM Compound: Gomisin B	Cytotoxicity against human SiHa cells assessed as reduction in cell viability measured after 48 hrs by SRB assay Cytotoxicity against human SiHa cells assessed as reduction in cell viability measured after 48 hrs by SRB assay	[PMID: 28818768]

Chemical Information

CAS No. 77881-08-4
Molecular Weight 514.56
Formula C₂₈H₃₄O₉
SMILES

C[C@H]1CC(C=C(OCO2)C2=C3OC)=C3C4=C(OC)C(OC)=C(OC)C=C4[C@H](OC(/C(C)=C\C)=O)[C@@]1(O)C
Synonyms

Angeloylgomisin P
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (278 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Teponno RB, et al. Recent advances in research on lignans and neolignans. Nat Prod Rep. 2016 Aug 25;33(9):1044-92. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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References

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Schinlignan B

All HIV Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Schinlignan B Related Classifications

HY-N15262 Related Classifications