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  3. Schinlignan B

Schinlignan B (Angeloylgomisin P) is a lignan with antioxidant, anti-HIV, anti-HBV activities, which is found in plants of the Schisandra genus. Schinlignan B is promising for research of antioxidant-associated diseases.

For research use only. We do not sell to patients.

Schinlignan B

Schinlignan B Chemical Structure

CAS No. : 77881-08-4

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Description

Schinlignan B (Angeloylgomisin P) is a lignan with antioxidant, anti-HIV, anti-HBV activities, which is found in plants of the Schisandra genus. Schinlignan B is promising for research of antioxidant-associated diseases[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
55.1 μM
Compound: Gomisin B
Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
[PMID: 28818768]
DU-145 IC50
64.7 μM
Compound: Gomisin B
Cytotoxicity against human DU145 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against human DU145 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
[PMID: 28818768]
HEK293 IC50
52 μM
Compound: Gomisin B
Cytotoxicity against HEK293 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against HEK293 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
[PMID: 28818768]
IMR-32 IC50
66.8 μM
Compound: Gomisin B
Cytotoxicity against human IMR32 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against human IMR32 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
[PMID: 28818768]
MDA-MB-231 IC50
60.5 μM
Compound: Gomisin B
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
[PMID: 28818768]
PANC-1 IC50
53.6 μM
Compound: Gomisin B
Cytotoxicity against human PANC1 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against human PANC1 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
[PMID: 28818768]
SiHa IC50
51.2 μM
Compound: Gomisin B
Cytotoxicity against human SiHa cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against human SiHa cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
[PMID: 28818768]
Molecular Weight

514.56

Formula

C28H34O9

CAS No.
SMILES

C[C@H]1CC(C=C(OCO2)C2=C3OC)=C3C4=C(OC)C(OC)=C(OC)C=C4[C@H](OC(/C(C)=C\C)=O)[C@@]1(O)C

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Schinlignan B
Cat. No.:
HY-N15262
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