2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3822):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-182249
    Aristeromycin 5′-diphosphate
    Aristeromycin (ArDP) 5′-diphosphate is a carbocyclic nucleotide analog of adenosine diphosphate (ADP). Aristeromycin 5′-diphosphate acts as a key intermediate in the synthesis of bioactive compounds.
    Aristeromycin 5′-diphosphate
  • HY-N3703
    Δ16-Adynerin gentiobioside
    Δ16-Adynerin gentiobioside is a natural steroid.
    Δ16-Adynerin gentiobioside
  • HY-179480
    G-quadruplex ligand 4
    G-quadruplex ligand 4 is a chromenone derivative and is a human telomerase reverse transcriptase (hTERT) G4 ligand. G-quadruplex ligand 4 downregulates hTERT expression and exhibits notable cytotoxicity towards triple-negative breast cancer (TNBC) cell lines. G-quadruplex ligand 4 can cause S/G2 cell cycle arrest and induce apoptosis. G-quadruplex ligand 4 downregulates the expression of hTERT, KRAS, and BCL-2. G-quadruplex ligand 4 can be used for the research of TNBC.
    G-quadruplex ligand 4
  • HY-N7923
    Retigeric acid A
    Retigeric acid A is a natural product that can be found in lichen.
    Retigeric acid A
  • HY-N16398
    Arenicolin B
    Arenicolin B is a C-glycosylated depside. Arenicolin B is promising for research of cancers and infections.
    Arenicolin B
  • HY-165564
    SM-8849
    SM-8849 is a thiazole derivative with anti-arthritis activity. SM-8849 specifically targets and inactivates T cells involved in delayed-type hypersensitivity (DTH) reactions, thereby inhibiting the core immunopathological process of arthritis, but has little effect on the humoral immune process such as antibody production. In a mouse arthritis model induced by Type II Collagen (HY-NP003), SM-8849 significantly alleviated clinical symptoms, reduced bone destruction and joint damage. SM-8849 can be used for the study of autoimmune diseases such as rheumatoid arthritis.
    SM-8849
  • HY-19375
    SB-235699
    SB-235699 is an active compound.
    SB-235699
  • HY-158733
    HR68
    HR68 is a derivative of Fenofibric acid (HY-B0760). HR68 is an anticancer agent.
    HR68
  • HY-N16825
    Spirasine III
    Spirasine III (9-Hydroxyspiredine) is a natural alkaloid.
    Spirasine III
  • HY-105531
    Sebriplatin
    Sebriplatin, a Cisplatin (HY-17394) analog, is a DNA inhibitor.
    Sebriplatin
  • HY-W021425S1
    D-Mannosamine-d2 hydrochloride
    D-Mannosamine-d2 (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal-d2) hydrochloride is a deuterium labeled D-Mannosamine hydrochloride (HY-W021425). D-Mannosamine ((2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal) hydrochloride is a six-carbon amino sugar and an amino derivative of D-mannose. D-Mannosamine hydrochloride can block mannose receptors.
    D-Mannosamine-d<sub>2</sub> hydrochloride
  • HY-N18353
    Hexadesacetyleuomynine
    Hexadesacetyleuomynine (Compound 15) is a nitrogen-containing dihydroagarofuran derivative found in the dried roots of Tripterygium wilfordii.
    Hexadesacetyleuomynine
  • HY-128401A
    Lysidine hydrochloride
    Lysidine (2-Lysylcytidine) hydrochloride is a lysine-containing Cytidine (HY-B0158) derivative commonly found at the wobble position of bacterial AUA codon-specific tRNA(Ile).
    Lysidine hydrochloride
  • HY-N17124
    Trijugin H
    Trijugin H is a natural sesquiterpene.
    Trijugin H
  • HY-N9836
    8,9-Dehydrothymol isobutyrate
    8,9-Dehydrothymol isobutyrate is a thymol (HY-N6810) derivative that can be naturally extracted from the essential oil of the trunk bark of Tetraclinis articulata (Vahl) Mast. This plant essential oil exhibits certain cytotoxicity and can be used as a research subject in the fields of natural product chemistry and the active components of plant essential oils.
    8,9-Dehydrothymol isobutyrate
  • HY-N17426
    (3β,5α,6α,22E)-Ergosta-7,22-diene-3,5,6-triol
    (3β,5α,6α,22E)-Ergosta-7,22-diene-3,5,6-triol is a natural product that can be found in animal bile.
    (3β,5α,6α,22E)-Ergosta-7,22-diene-3,5,6-triol
  • HY-W028108
    Piperonyl alcohol
    		99.78%
    Piperonyl alcohol is a benzodioxole derivative. It is biocompatible and can be used in chemical synthesis as an initiator.
    Piperonyl alcohol
  • HY-N9838
    1-Methyleffusol
    1-Methyleffusol is a natural phenolic compound.
    1-Methyleffusol
  • HY-106716
    SR 41378
    SR 41378 is an orally active aminopyrazine derivative. SR 41378 has anticonvulsant, antianxiety and hypnotic activities.
    SR 41378
  • HY-N2704
    1H-2,10a-Ethanophenanthrene, kaur-16-en-18-oic acid deriv.
    1H-2,10a-Ethanophenanthrene, kaur-16-en-18-oic acid deriv. is a derivated compound isolated from the Pteridaceae plants of Costa Rica .
    1H-2,10a-Ethanophenanthrene, kaur-16-en-18-oic acid deriv.