2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10875):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-Y0781S6
    Pyruvic acid-13C-4
    Pyruvic acid-13C-4 (Acetylformic acid-13C-4) is the 13C-labeled Pyruvic acid (HY-Y0781). Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats.
    Pyruvic acid-<sup>13</sup>C-4
  • HY-143666S
    DPPI-3,4,5-P3-d62 sodium
    DPPI-3,4,5-P3-d62 (sodium) is the deuterium labeled DPPI-3,4,5-P3 sodium.
    DPPI-3,4,5-P3-d<sub>62</sub> sodium
  • HY-19733S1
    Lumateperone-d4 tosylate
    Lumateperone-d4 tosylate (ITI-007-d4 tosylate) is the deuterium labeled Lumateperone tosylate (HY-19733). Lumateperone (ITI-007) tosylate is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone tosylate has anticancer activity and can also be used in studies of psychiatric disorders such as schizophrenia.
    Lumateperone-d<sub>4</sub> tosylate
  • HY-13570S1
    Betamethasone-d5-1
    Betamethasone-d5-1 is deuterium labeled Betamethasone. Betamethasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activities. Betamethasone accelerates fetal lung maturation and induces gene expression and apoptosis.
    Betamethasone-d<sub>5</sub>-1
  • HY-18981S
    Decursin-d6
    Decursin-d6 ((+)-Decursin-d6) is the deuterium labeled Decursin (HY-18981). Decursin ((+)-Decursin) is a potent anti-tumor agent. Decursin also is a cytotoxic agent and a potent protein kinase C activator. Decursin induces apoptosis and cell cycle arrest at G1 phase. Decursin decreases the expression of CDK2, CDK4, CDK6, cyclin D1 protein at 48 h. Decursin inhibits cell proliferation and migration. Decursin shows anti-tumor, anti-inflammatory and analgesic activities.
    Decursin-d<sub>6</sub>
  • HY-50898S5
    Lapatinib-13C,d7
    Lapatinib-13C,d7 (GW572016-13C,d7) is the deuterium and 13C-labeled Lapatinib (HY-50898). Lapatinib (GW572016) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively.
    Lapatinib-</sub><sup>13</sup>C,d<sub>7</sub>
  • HY-W702077
    3-Chloro-2-methyl-1,1'-biphenyl-d5
    3-Chloro-2-methyl-1,1'-biphenyl-d5 (3-Chloro-2-methylbiphenyl-d5) is the deuterium labeled 3-Chloro-2-methyl-1,1'-biphenyl (HY-W094186).
    3-Chloro-2-methyl-1,1'-biphenyl-d<sub>5</sub>
  • HY-B0553S
    Methazolamide-d6
    Methazolamide-d6 is the deuterium labeled Methazolamide. Methazolamide (L584601) is a sulfonamide derivative used as a carbonic anhydrase inhibitor with a Ki of 14 nM for human carbonic anhydrase II. Methazolamide, an intraocular pressure-lowering agent, reduces intraocular pressure elevations associated with glaucoma and other ocular disorders.
    Methazolamide-d<sub>6</sub>
  • HY-B0546AS
    Procaine-d4 hydrochloride
    Procaine-d4 (hydrochloride) is the deuterium labeled Procaine hydrochloride. Procaine hydrochloride is a DNA-demethylating agent. Procaine hydrochloride acts through multiple targets and has a slow onset and a short duration of action.
    Procaine-d<sub>4</sub> hydrochloride
  • HY-W007328S
    5-Methoxyindole-d3
    5-Methoxyindole-d3 is the deuterium labeled 5-Methoxyindole (HY-W007328). 5-Methoxyindole is an endogenous compound with significant biological activity, which is produced by the metabolism of L-tryptophan. 5-Methoxyindole can be used as a drug intermediate to synthesize 5-methoxytryptophan and N-acetyl 5-methoxytryptamine, and it exhibits anti-cancer and anti-inflammatory activities.
    5-Methoxyindole-d<sub>3</sub>
  • HY-N7092AS
    L-Fructose-1-13C
    L-Fructose-1-13C is the 13C labeled L-Fructose.
    L-Fructose-1-<sup>13</sup>C
  • HY-W750538
    Flumazenil Carboxylic Acid-d3
    Flumazenil Carboxylic Acid-d3 is the deuterium labeled Flumazenil Carboxylic Acid.
    Flumazenil Carboxylic Acid-d<sub>3</sub>
  • HY-W751834
    6-Amino-5-nitropyrimidine-2,4(1H,3H)-dione-13C3
    6-Amino-5-nitropyrimidine-2,4(1H,3H)-dione-13C3 (NSC 99321-13C3) is the 13C-labeled 6-Amino-5-nitropyrimidine-2,4(1H,3H)-dione (HY-W016913).
    6-Amino-5-nitropyrimidine-2,4(1H,3H)-dione-<sup>13</sup>C<sub>3</sub>
  • HY-136380S
    Clodinafop-propargyl-13C6
    Clodinafop-propargyl-13C6 is the 13C-labeled Clodinafop-propargyl (HY-136380). Clodinafop-propargyl, an aryloxyphenoxy-propionate herbicide, is used for postemergence control of annual grasses in cereals. Clodinafop-propargyl has organ toxicity and developmental toxicity.
    Clodinafop-propargyl-<sup>13</sup>C<sub>6</sub>
  • HY-D0839S1
    Tetradecyltrimethylammonium-d29 bromide
    Tetradecyltrimethylammonium-d29 (bromide) is the deuterium labeled Tetradecyltrimethylammonium (bromide). Tetradecyltrimethylammonium bromide, an organic building block, is a cationic surfactant with asymmetrical structure.
    Tetradecyltrimethylammonium-d<sub>29</sub> bromide
  • HY-W768514
    (3b,22E)-Ergosta-5,7,22-triene-3,24,25-triol-d3
    (3b,22E)-Ergosta-5,7,22-triene-3,24,25-triol-d3 is the deuterium labeled (3b,22E)-Ergosta-5,7,22-triene-3,24,25-triol.
    (3b,22E)-Ergosta-5,7,22-triene-3,24,25-triol-d<sub>3</sub>
  • HY-W009412S
    D-Phenyl-alanine-N-t-Boc-d5
    		99.85%
    D-Phenyl-alanine-N-t-Boc-d5 is the deuterium labeled D-Phenyl-alanine-N-t-Boc.
    D-Phenyl-alanine-N-t-Boc-d<sub>5</sub>
  • HY-N0059S6
    D-Arabinose-d6
    D-Arabinose-d6 is the deuterium labeled D-Arabinose (HY-N0059). D-Arabinose is is an orally active antidepressant and a growth inhibitor of C. elegans (IC50 is 7.5 mM). D-Arabinose can penetrate the blood-brain barrier, selectively interfere with the metabolism of D-ribose and D-fructose, and inhibit the growth of nematodes. D-Arabinose can also inhibit the synthesis of cell biofilm and exert antibacterial activity. D-Arabinose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, inducing CRTC1 transcription, exerts antidepressant-like activity. D-Arabinose is the ring-opened form of the aldopentose D-?Arabinose (HY-N7082).
    D-Arabinose-d<sub>6</sub>
  • HY-W743138
    Piperidin-4-yl ethylcarbamate-d4
    Piperidin-4-yl ethylcarbamate-d4 is the deuterium labeled Piperidin-4-yl ethylcarbamate (HY-W558718).
    Piperidin-4-yl ethylcarbamate-d<sub>4</sub>
  • HY-B0574S2
    Mefenamic acid-13C6
    Mefenamic acid-13C6 is the 13C-labeled Mefenamic acid. Mefenamic acid is a BBB-permeable non-steroidal anti-inflammatory agent, acting as a competitive inhibitor of hCOX-1 and hCOX-2, with IC50s of 40 nM and 3 μM for hCOX-1 and hCOX-2, respectively.
    Mefenamic acid-<sup>13</sup>C<sub>6</sub>