Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11128)
Related Products (11128)
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1-Decanol-d2-2
0 ImagesCat. No.: HY-Y1004S6CAS No.: 1335435-63-6Synonyms: Decyl alcohol-d2-21-Decanol-d2-2 is deuterated labeled 1-Decanol (HY-Y1004). 1-Decanol is used in the production of lubricants, surfactants, plasticizers and solvents. It has also been used to study the thermal properties of polymeric monolithic stationary phases and to enhance homopolyglycine acceptor function. Used in cosmetics, daily flavors, and food flavors.
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p-Cresol sulfate-d4 potassium
0 ImagesCat. No.: HY-W654121Synonyms: p-Tolyl sulfate-d4 potassium
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N-Acetyl-S-(2,4-dimethylphenyl)cysteine-d3
0 ImagesCat. No.: HY-W701153N-Acetyl-S-(2,4-dimethylphenyl)cysteine-d3 is the deuterium labeled N-Acetyl-S-(2,4-dimethylphenyl)cysteine.
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Bis(butoxyethyl) phosphate-d8
0 ImagesCat. No.: HY-W653928CAS No.: 2305665-16-9Bis(butoxyethyl) phosphate-d8 is a deuterium labeled Bis(butoxyethyl) phosphate.
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7α,24(R/S)-Dihydroxycholesterol-d7
0 ImagesCat. No.: HY-146784SCAS No.: 2260669-20-17α,24(R/S)-Dihydroxycholesterol-d7 is deuterium labeled 7α,24(R/S)-Dihydroxycholesterol.
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PCB118-13C12
0 ImagesCat. No.: HY-W748332CAS No.: 104130-40-7Synonyms: CDE-99-13C12; PCB No 118-13C12; 2,3',4,4',5-Pentachlorobiphenyl-13C12PCB118-13C12 (CDE-99-13C12; PCB No 118-13C12; 2,3',4,4',5-Pentachlorobiphenyl-13C12) is 13C labeled PCB118.
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3-Hydroxy carvedilol-d5
0 ImagesCat. No.: HY-132499SCAS No.: 1329836-56-73-Hydroxy Carvedilol-d5 is the deuterium labeled 3-Hydroxy Carvedilol.
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Fenoxycarb-d3
0 ImagesCat. No.: HY-W718787CAS No.: 2468639-22-5Fenoxycarb-d3 is deuterium labeled Fenoxycarb.
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Elinzanetant-d3
0 ImagesCat. No.: HY-109171SSynonyms: NT-814-d3; BAY3427080-d3Elinzanetant-d3 (NT-814-d3) is deuterium labeled Elinzanetant. Elizanetant (NT-814) is an orally active, selective NK-1,3 receptor antagonist. Elizanetant can reduce the levels of estradiol and progesterone, and is used in the study of vascular motor symptoms and sleep disorders related to menopause in women.
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3,3′,4,4′-Tetrabromo diphenyl ether-13C12
0 ImagesCat. No.: HY-W715357SCAS No.: 1401355-55-23,3′,4,4′-Tetrabromo diphenyl ether-13C12 is 13C labeled 4,4'-Oxybis(1,2-dibromobenzene).
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1,2,3,4-Tetrahydronaphthalene-d4
0 ImagesCat. No.: HY-Y1805SCAS No.: 92633-06-2Synonyms: Tetralin solvent-d41,2,3,4-Tetrahydronaphthalene-d4 (Tetralin solvent-d4) is the deuterium labeled 1,2,3,4-Tetrahydronaphthalene (HY-Y1805).
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Nitisinone-d3
0 ImagesCat. No.: HY-B0607SSynonyms: NTBC-d3; Nitisone-d3; SC0735-d3Nitisinone-d3 (NTBC-d3) is deuterium labeled Nitisinone. Nitisinone is an orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with an IC50 of 173 nM. Nitisinone promotes tyrosine accumulation in a dose-dependent manner. nitisinone can be used in studies of hereditary tyrosinemia type 1 (HT-1) (a rare genetic disorder) and albinism.
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Pantoprazole-d4
0 ImagesCat. No.: HY-17507S4CAS No.: 934294-71-0Synonyms: BY1023-d4; SKF96022-d4Pantoprazole-d4 (BY1023-d4) is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI). Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142).
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Pyroxsulam Metabolite ADTP-d6
0 ImagesCat. No.: HY-W097565SSynonyms: 5,7-Dimethoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-amine-d6Pyroxsulam Metabolite ADTP-d6 (5,7-Dimethoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-amine-d6) is deuterium labeled 5,7-Dimethoxy-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine.
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Fosamprenavir-13C6
0 ImagesCat. No.: HY-78726S2Synonyms: Amprenavir phosphate-13C6; GW 433908-13C6Fosamprenavir-13C6 is the 13C-labeled Fosamprenavir (HY-78726). Fosamprenavir is an orally active inhibitor targeting HIV-1 protease and is a prodrug of Amprenavir (HY-17430). Fosamprenavir is hydrolyzed into Amprenavir (VX-478) by cell phosphatases in the intestinal epithelium. Amprenavir binds to the active site of HIV-1 protease, preventing the processing of viral gag and gag-pol polyprotein precursors, thereby inhibiting the formation of mature infectious virus particles and exerting anti-HIV-1 infection activity. Fosamprenavir can be used for the study of human immunodeficiency virus (HIV-1) infection.
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Imidapril-d3 (hydrochloride)
0 ImagesCat. No.: HY-B1451SCAS No.: 1356017-30-5Imidapril-d3 hydrochloride (TA-6366-d3) is the deuterium labeled Imidapril hydrochloride. Imidapril hydrochloride (TA-6366) is an orally active dual inhibitor of angiotensin-converting enzyme (ACE) and MMP-9. Imidapril hydrochloride inhibits lipopolysaccharide-induced phosphorylation of c-Jun, MKK4 and JNK in monocytes, and downregulates the production of specific inflammatory factors such as TNF-α and IP-10, thereby exerting anti-inflammatory activity. Imidapril hydrochloride also effectively ameliorates mesangial expansion and reduces urinary albumin excretion by inhibiting angiotensin AngII production, lowering glomerular pressure and oxidative stress, thus delaying disease progression. Imidapril hydrochloride can also directly bind to the active site of MMP-9 to inhibit gelatinase activity, and suppress the enlargement of cerebral aneurysms without altering systemic blood pressure. Imidapril hydrochloride is widely applicable to related studies on autoimmune glomerulonephritis, diabetic nephropathy, cerebral aneurysms and other conditions.
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5-Methylcytidine 5′-triphosphate-15N2, 13C trisodium
0 ImagesCat. No.: HY-147338S1Synonyms: 5-Methyl-CTP-15N2, 13C trisodium5-Methylcytidine 5′-triphosphate-15N2, 13C trisodium (5-Methyl-CTP-15N2, 13C trisodium) is the 13C, 15N-labeled 5-Methylcytidine 5′-triphosphate trisodium (HY-147338A). 5-Methylcytidine 5′-triphosphate trisodium is a modified cytidine triphosphate nucleotide. 5-Methylcytidine 5′-triphosphate trisodium serves as a modified nucleotide substrate for in vitro transcription, partially or completely replacing CTP. 5-Methylcytidine 5′-triphosphate trisodium enhances mRNA stability and translation efficiency, and reduces activation of the innate immune system. 5-Methylcytidine 5′-triphosphate trisodium is used in RNA synthesis-related research.
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Taurocholic acid-d5 sodium
0 ImagesCat. No.: HY-W653893Taurocholic acid-d5 (sodium) is deuterium labeled Taurocholic acid (sodium). Taurocholic acid sodium (Sodium taurocholate) has marked bioactive effects such as an inhibitory potential against hepatic artery ligation induced biliary damage by upregulation of VEGF-A expression. Taurocholic acid sodium has immunoregulation effect.
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Crizotinib-d8
0 ImagesCat. No.: HY-50878S1CAS No.: 1523579-82-9Synonyms: PF-02341066-d8Crizotinib-d8 (PF-02341066-d8) is deuterium labeled Crizotinib. Crizotinib (PF-02341066) is an orally bioavailable, ATP-competitive ALK and c-Met inhibitor with IC50s of 20 and 8 nM, respectively. Crizotinib inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC50s of 24 and 11 nM in cell-based assays, respectively. Crizotinib is also a ROS1 inhibitor. Crizotinib has effective tumor growth inhibition.
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(-)-Menthone-d8
0 ImagesCat. No.: HY-N1920SCAS No.: 244023-68-5Synonyms: L-Menthone-d8(-)-Menthone-d8 (L-Menthone-d8) is deuterated labeled L-Menthone.
