PI5P4K Degrader
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LRK-4189
0 ImagesCat. No.: HY-175751CAS No.: 3063346-83-5LRK-4189 is an first-in-class, orally active CRBN-dependent PIP4K2C PROTAC degrader. LRK-4189-mediated degradation of PIP4K2C leads to intrinsic cell death and upregulation of the STAT1 pathway and signaling in microsatellite stable colorectal cancer (MSS CRC) cells. LRK-4189 can be used for the research of microsatellite-stable colorectal cancer.
