1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Protoporphyrinogen IX oxidase

Protoporphyrinogen IX oxidase

Protoporphyrinogen IX oxidase (PPO) catalyzes the oxidation of protoporphyrinogen IX to protoporphyrinogen IX. PPO is also a target of diphenyl ether herbicides. In plants, there are two PPO encoding genes, namely PPO1 and PPO2.

Protoporphyrinogen IX oxidase Related Products (34):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-173015
    PPO-IN-16
    Inhibitor
    PPO-IN-16 (Compound D5) is a PPO inhibitor and herbicide with a Ki of 33.7 nM against Nicotiana tabacum PPO (NtPPO). PPO-IN-16 has a broad herbicidal spectrum and exhibits good safety on crops such as wheat, rice, and peanut.
    PPO-IN-16
  • HY-183559
    Herbicidal agent 16
    Inhibitor
    Herbicidal agent 16 is a herbicide and Protoporphyrinogen IX oxidase (PPO) inhibitor with an IC50 of 15.1 nM and Kd of 24.89 nM. Herbicidal agent 16 can be used for research on herbicides.
    Herbicidal agent 16
  • HY-119176R
    Oxyfluorfen (Standard)
    Inhibitor
    Oxyfluorfen (Standard) is the analytical standard of Oxyfluorfen. This product is intended for research and analytical applications. Oxyfluorfen is a pre- and post-emergence diphenyl ether herbicide to control annual broad-leaved and grass weeds. Oxyfluorfen is a protoporphyrinogen oxidase inhibitor and inhibits photosynthesis by blocking chlorophyll synthesis. Oxyfluorfen can inhibit cell growth. Oxyfluorfen induces DNA damage and exhibits toxicity toward aquatic organisms such as Paramisgurnus dabryanus. Oxyfluorfen has genome-level deleterious effects on fish that can lead to stunted skeletal growth. Oxyfluorfen induces transverse limb deficiency or craniosynostosis.
    Oxyfluorfen (Standard)
  • HY-172215
    PPO-IN-18
    Inhibitor
    PPO-IN-18 (Compound g13) is the inhibitor for protoporphyrinogen oxidase (PPO) that inhibits Echinochloa crus-galli PPO (EcPPO) with an IC50 of 0.109 μM. PPO-IN-18 exhibits herbicidal effect against E. crus-galli, Digitaria sanguinalis, Setaria faberi, Ipomoea nil, Chenopodium quinoa, and Abutilon theophrasti, without significant toxicity in crops (150-300 g ai/ha).
    PPO-IN-18
  • HY-180894
    PPO-IN-24
    Inhibitor
    PPO-IN-24 (compound P12) is a lipophilic protoporphyrinogen oxidase IX (PPO) inhibitor. PPO-IN-24 can be used as a herbicide for weed control.
    PPO-IN-24
  • HY-178107
    PPO-IN-21
    Inhibitor
    PPO-IN-21 (Compound A20) is a protoporphyrinogen IX oxidase (PPO) inhibitor with a Ki of 15.2 nM for Nicotiana tabacum PPO. PPO-IN-21 has inhibitory activity against various weeds (including monocots and dicots). PPO-IN-21 can be used as herbicide.
    PPO-IN-21
  • HY-157471
    PPO-IN-7
    Inhibitor
    PPO-IN-7 (compound 35) is a potent inhibitor of protoporphyrinogen oxidase (PPO). PPO-IN-7 shows herbicidal activity.
    PPO-IN-7
  • HY-W748338
    Flumiclorac-pentyl
    Inhibitor
    Flumiclorac-pentyl is a herbicide and NtPPO inhibitor, with a Ki value of 46.02 nM against NtPPO. Flumiclorac-pentyl exhibits herbicidal activity against Abutilon theophrasti, Amaranthus retroflexus, Portulaca oleracea, Setaria viridis, Digitaria sanguinalis and Echinochloa crusgalli.
    Flumiclorac-pentyl
  • HY-B2010R
    Fomesafen (Standard)
    Inhibitor
    Fomesafen (Standard) is the analytical standard of Fomesafen (HY-B2010). This product is intended for research and analytical applications. Fomesafen is an orally active herbicide. Fomesafen inhibits protoporphyrinogen oxidase (PPO). Fomesafen induces Apoptosis and increases ROS. Fomesafen exhibits developmental toxicity, immunotoxicity, and neurotoxicity. It induces precancerous lesions in the liver and hepaturoporphyria in mice. Fomesafen is used to control broadleaf weeds in soybean fields, rubber plantations, and orchards.
    Fomesafen (Standard)
  • HY-157470
    PPO-IN-6
    Inhibitor
    PPO-IN-6 is a protoporphyrinogen oxidase (PPO) inhibitor that blocks the production of heme and chlorophyll. Pop-in-6 can be used IN the detection and research of cancer and other diseases.
    PPO-IN-6
  • HY-161951
    PPO-IN-15
    Inhibitor
    PPO-IN-15 (compound (R)-I-5) is a protoporphyrinogen IX oxidase (PPO) inhibitor that is effective against resistant weeds and safer in wheat and rice.
    PPO-IN-15
  • HY-173058
    NtPPO-IN-1
    Inhibitor
    NtPPO-IN-1 (Compound A4) is the inhibitor for Nicotiana tabacum PPO (NtPPO) with a Ki of 9.05 nM. NtPPO-IN-1 exhibits herbicidal activity against Setaria viridis, Echinochloa crus-galli, Digitaria sanguinalis, Amaranthus retroflexus, Abutilon theophrasti and Portulaca oleracea, and exhibits 30-50% injury to corn and rice (150 g a.i./ha).
    NtPPO-IN-1
  • HY-136513
    Bifenox
    Inhibitor 99.77%
    Bifenox (MC-4379) is a nitrophenyl ether herbicide. Bifenox disrupts cellular membrane, inhibits photosynthesis and inhibits the protoporphyrinogen oxidase. Bifenox increases the ROS production in the microalgae Chlamydomonas reinhardtii.
    Bifenox
  • HY-178026
    HPPD/PPO-IN-1
    Inhibitor
    HPPD/PPO-IN-1 (Compound B14) is dual-functional inhibitor of HPPD and PPO with IC50s of 0.12  μM and 0.51 μM for Arabidopsis thaliana HPPD and Nicotiana tabacum PPO, respectively. HPPD/PPO-IN-1 has broad-spectrum herbicidal activity against weeds with a crop safety to peanuts and cotton. HPPD/PPO-IN-1 can be used for the development of environmentally friendly herbicides.
    HPPD/PPO-IN-1