2. Signaling Pathways
  3. Epigenetics
  4. SF3B1
  5. SF3B1 Modulator

SF3B1 Modulator

SF3B1 Modulator (1):

Cat. No. Product Name Effect Purity
  • HY-168534
    WX-02-23
    		Modulator 99.88%
    WX-02-23 is a small-molecule probe that stereoselectively and site-specifically binds to C258 of FOXA1 and C1111 of SF3B1. WX-02-23 remodels FOXA1's chromatin binding and pioneer activity in a DNA-dependent manner, disrupts spliceosome assembly, and enhances the thermal stability of SF3B1. WX-02-23 inhibits tumor cell proliferation and induces apoptosis. WX-02-23 can be used for research on cancers such as prostate cancer.