γ-secretase Control
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(R)-JNJ-40418677
0 Images(R)-JNJ-40418677 is the R-enantiomer of JNJ-40418677 (HY-100604).
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(1R,3S)-Compound E
0 Images(1R,3S)-Compound E is the isomer of Compound E (HY-14176), and can be used as an experimental control. Compound E is a γ-secretase inhibitor. Compound E bloks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC50s of 0.24, 0.37, 0.32 nM, respectively.
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(R)-JNJ-40418677 (Standard)
0 Images(R)-JNJ-40418677 (Standard) is the analytical standard of (R)-JNJ-40418677 (HY-100604A). This product is intended for research and analytical applications. (R)-JNJ-40418677 is the R-enantiomer of JNJ-40418677 (HY-100604).
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