A 62176 hydrochloride
A 62176 hydrochloride is a compound that targets DNA topoisomerase II and has the activity of inhibiting purine synthesis in cancer cells. A 62176 hydrochloride interferes with c-MYC mRNA expression by interacting with G-quadruplex. The main mechanism of action of A 62176 hydrochloride is by displacing nucleosomes from the quadruplex of non-template strand rDNA, resulting in rapid redistribution of nucleosomes. The application potential of A 62176 hydrochloride is that it causes DNA damage and relies on BRCA1/2-mediated homologous recombination and DNA-PK-mediated non-homologous end-joining pathways to repair the damage.
For research use only. We do not sell to patients.
- CAS No.: 111783-54-1
- Formula: C20H17ClFN3O4
- Molecular Weight:417.82
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Biological Activity
Chemical Information
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CAS No. 111783-54-1
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Molecular Weight 417.82
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Formula C20H17ClFN3O4
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SMILES
O=C(C1=CN2C3=C(OC4=C2C(C1=O)=CC(F)=C4N5CCC(C5)N)C=CC=C3)O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
A 62176 hydrochloride Related Classifications
HY-120750 Related Classifications
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