ABD459
ABD459 is a CB1 receptor antagonist with significant effects on regulating food intake and sleep-wake cycles. ABD459 completely displaces CB1 agonist CP99540 (Ki = 8.6 nM) and antagonizes CP55940-induced GTPγS binding (KB = 7.7 nM). ABD459 may specifically modulate endogenous cannabinoid release through cholinergic activity and plays a role in attention and arousal regulation. ABD459 is suitable for research in neurological disorders.
For research use only. We do not sell to patients.
- CAS No.: 1047670-51-8
- Formula: C24H17BrCl2N2O2
- Molecular Weight:516.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1047670-51-8
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Molecular Weight 516.21
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Formula C24H17BrCl2N2O2
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SMILES
O=C(C1=NN(C(C2=CC=C(Br)C=C2)=C1C)C3=CC=C(C=C3Cl)Cl)C4=CC=C(C=C4)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)