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Cat. No.: HY-156030

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AChE-IN-40

AChE-IN-40 (Compound 5C) is an AChE inhibitor (IC₅₀: 120 nM). AChE-IN-40 can be used for research of Alzheimer's disease.

For research use only. We do not sell to patients.

Formula: C₂₃H₂₇NO₄
Molecular Weight:381.46

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

AChE-IN-40 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

AChE-IN-40 (Compound 5C) is an AChE inhibitor (IC₅₀: 120 nM). AChE-IN-40 can be used for research of Alzheimer's disease^[1].

IC₅₀ & Target

0.12, 1.01 μM (AChE, BChE)^[1]

All Cholinesterase (ChE) Isoforms :

AChE
BChE

Chemical Information

Molecular Weight 381.46
Formula C₂₃H₂₇NO₄
SMILES

O=C1/C(CC2=C1C=C(OC)C(OC)=C2)=C/C3=CC=CC(OCCCN(C)C)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Etemadi A, et al. Design, Synthesis, and Biological Evaluation of Novel Indanone Derivatives as Cholinesterase Inhibitors for Potential Use in Alzheimer's Disease. Chem Biodivers. 2023 Aug;20(8):e202300075. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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