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  6. Acronycine

Acronycine (Acronine) is an acridone alkaloid.

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Acronycine

Acronycine Chemical Structure

CAS No. : 7008-42-6

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Acronycine Related Antibodies

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Description

Acronycine (Acronine) is an acridone alkaloid[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
>100 μM
Compound: Acronycine
Inhibitory concentration of compound against proliferation of lung carcinoma A549 cell line
Inhibitory concentration of compound against proliferation of lung carcinoma A549 cell line
[PMID: 12031316]
A549 IC50
>100 μM
Compound: Acronycine
In vitro cytotoxic activity against human lung A549 cell line)
In vitro cytotoxic activity against human lung A549 cell line)
[PMID: 12036369]
A549 IC50
100 μM
Compound: Acronycine
Inhibitory concentration of compound against proliferation of lung carcinoma A549 cell line
Inhibitory concentration of compound against proliferation of lung carcinoma A549 cell line
[PMID: 12031316]
HaCaT IC50
3.2 μM
Compound: 1, Acronycine
Antiproliferative activity against human HaCaT cells assessed as dispersed cells after 48 hrs by phase-contrast microscopic analysis
Antiproliferative activity against human HaCaT cells assessed as dispersed cells after 48 hrs by phase-contrast microscopic analysis
[PMID: 20850910]
HCT-116 IC50
>100 μM
Compound: Acronycine
In vitro cytotoxic activity against human colon HCT116 cell line
In vitro cytotoxic activity against human colon HCT116 cell line
[PMID: 12036369]
HL-60 IC50
26.2 μM
Compound: acronycine
Ability to inhibit human leukemic HL-60 cell growth in culture
Ability to inhibit human leukemic HL-60 cell growth in culture
[PMID: 1635067]
HL-60 IC50
26.2 μM
Compound: Acronycine
In vitro antitumor activity against HL60 (Human leukemia) cells.
In vitro antitumor activity against HL60 (Human leukemia) cells.
10.1016/S0960-894X(97)00117-0
HRT-18 cell line IC50
>100 μM
Compound: Acronycine
In vitro cytotoxic activity against human colon HRT-18 cell line
In vitro cytotoxic activity against human colon HRT-18 cell line
[PMID: 12036369]
HT-29 IC50
>100 μM
Compound: Acronycine
Inhibitory concentration of compound against proliferation of colon carcinoma HT-29 cell line
Inhibitory concentration of compound against proliferation of colon carcinoma HT-29 cell line
[PMID: 12031316]
HT-29 IC50
>100 μM
Compound: Acronycine
In vitro cytotoxic activity against human colon HT-29 cell line
In vitro cytotoxic activity against human colon HT-29 cell line
[PMID: 12036369]
KB 3-1 IC50
3.7 μM
Compound: 1
Antiproliferative activity against human KB-3-1 cell line by MTT assay
Antiproliferative activity against human KB-3-1 cell line by MTT assay
[PMID: 16722658]
KB 3-1 IC50
3.7 μM
Compound: 1
Cytotoxicity against human KB-3-1 cells after 96 hrs by MTT assay
Cytotoxicity against human KB-3-1 cells after 96 hrs by MTT assay
[PMID: 18947222]
KB 3-1 IC50
3.7 μM
Compound: 1
Cytotoxicity against human KB-3-1 cells after 96 hrs by MTT assay
Cytotoxicity against human KB-3-1 cells after 96 hrs by MTT assay
[PMID: 25360689]
L1210 IC50
10.4 μM
Compound: 1
Cytotoxicity against mouse L1210 cells after 48 hrs by MMT assay
Cytotoxicity against mouse L1210 cells after 48 hrs by MMT assay
[PMID: 10096866]
L1210 IC50
10.4 μM
Compound: 10
Cytotoxicity against mouse L1210 cells
Cytotoxicity against mouse L1210 cells
[PMID: 19191562]
L1210 IC50
19.9 μM
Compound: 1
In vitro inhibition of L1210 cell proliferation.
In vitro inhibition of L1210 cell proliferation.
[PMID: 10882366]
L1210 IC50
21 μM
Compound: Acronycine
Cytotoxicity against mouse L1210 cells after 48 hrs by coulter counter method
Cytotoxicity against mouse L1210 cells after 48 hrs by coulter counter method
[PMID: 29324343]
L1210 IC50
23 μM
Compound: 1
Antiproliferative activity against mouse L1210 cell line by MTT assay
Antiproliferative activity against mouse L1210 cell line by MTT assay
[PMID: 16722658]
L1210 IC50
23 μM
Compound: 1
Cytotoxicity against mouse L1210 cells after 48 hrs by MTT assay
Cytotoxicity against mouse L1210 cells after 48 hrs by MTT assay
[PMID: 18947222]
L1210 IC50
23 μM
Compound: 1
Cytotoxicity against mouse L1210 cells after 48 hrs by MTT assay
Cytotoxicity against mouse L1210 cells after 48 hrs by MTT assay
[PMID: 25360689]
L1210 IC50
23 μM
Compound: 1
Cytotoxicity against mouse L1210 cells assessed as cell growth inhibition
Cytotoxicity against mouse L1210 cells assessed as cell growth inhibition
[PMID: 35717872]
L1210 IC50
24.1 μM
Compound: 1
Compound was tested in vitro for cytotoxicity on L1210 leukemic cells by using MTT assay.
Compound was tested in vitro for cytotoxicity on L1210 leukemic cells by using MTT assay.
[PMID: 8941390]
L1210 IC50
25 μM
Compound: 1
Cytotoxicity against mouse L1210 cells after 48 hrs by MMT assay
Cytotoxicity against mouse L1210 cells after 48 hrs by MMT assay
[PMID: 9514007]
L1210 IC50
27 μM
Compound: Acronycine
Inhibitory concentration of compound against proliferation of murine leukemia L1210 cell line
Inhibitory concentration of compound against proliferation of murine leukemia L1210 cell line
[PMID: 12031316]
L1210 IC50
27 μM
Compound: Acronycine
In vitro cytotoxic activity against murine leukemia cell line L1210
In vitro cytotoxic activity against murine leukemia cell line L1210
[PMID: 12036369]
Molecular Weight

321.37

Formula

C20H19NO3
CAS No.
SMILES

O=C1C2=C(N(C3=C4C=CC(C)(OC4=CC(OC)=C13)C)C)C=CC=C2
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Acronycine Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Acronycine7008-42-6AcronineOthersacridone alkaloidInhibitorinhibitorinhibit

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