Actinine-d9 chloride
Based on 1 Customer Validation
Actinine-d9 chloride is the deuterium labeled Actinine chloride. Actinine chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat.
For research use only. We do not sell to patients.
- Purity: 98.01%
- CAS No.: 85806-17-3
- Formula: C7H7D9ClNO2
- Molecular Weight:190.72
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 85806-17-3
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Unlabeled Cas 6249-56-5
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Appearance Solid
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Molecular Weight 190.72
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Formula C7H7D9ClNO2
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Color White to off-white
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SMILES
[2H]C([N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])CCCC(O)=O)([2H])[2H].[Cl-]
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Synonyms
γ-Butyrobetaine-d9 hydrochloride; Deoxycarnitine-d9 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 25 mg/mL (131.08 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Koeth RA, et al. γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO. Cell Metab. 2014 Nov 4;20(5):799-812. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.2433 mL | 26.2164 mL | 52.4329 mL | 131.0822 mL |
| 5 mM | 1.0487 mL | 5.2433 mL | 10.4866 mL | 26.2164 mL | |
| 10 mM | 0.5243 mL | 2.6216 mL | 5.2433 mL | 13.1082 mL | |
| 15 mM | 0.3496 mL | 1.7478 mL | 3.4955 mL | 8.7388 mL | |
| 20 mM | 0.2622 mL | 1.3108 mL | 2.6216 mL | 6.5541 mL | |
| 25 mM | 0.2097 mL | 1.0487 mL | 2.0973 mL | 5.2433 mL | |
| 30 mM | 0.1748 mL | 0.8739 mL | 1.7478 mL | 4.3694 mL | |
| 40 mM | 0.1311 mL | 0.6554 mL | 1.3108 mL | 3.2771 mL | |
| 50 mM | 0.1049 mL | 0.5243 mL | 1.0487 mL | 2.6216 mL | |
| 60 mM | 0.0874 mL | 0.4369 mL | 0.8739 mL | 2.1847 mL | |
| 80 mM | 0.0655 mL | 0.3277 mL | 0.6554 mL | 1.6385 mL | |
| 100 mM | 0.0524 mL | 0.2622 mL | 0.5243 mL | 1.3108 mL |
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