AFD-21 maleate
AFD-21 maleate is a drug with antiarrhythmic activity. AFD-21 maleate inhibits sodium channels by binding to sodium channels in an inactive state, with both use-dependent and voltage-dependent effects. The unbinding rate of AFD-21 maleate is similar to that of Class I antiarrhythmic drugs with moderate kinetics. AFD-21 maleate can cause a slight prolongation of the action potential duration and significantly reduce the maximum rise rate of the action potential at certain concentrations. AFD-21 maleate also showed use-dependent blocking effects as stimulation frequency increased.
For research use only. We do not sell to patients.
- CAS No.: 99465-44-8
- Formula: C28H39NO5
- Molecular Weight:469.61
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 99465-44-8
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Molecular Weight 469.61
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Formula C28H39NO5
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SMILES
OC(C1=CC=CC=C1)(CCCN(CC(C)C)CC(C)C)C2=CC=CC=C2.O=C(O)/C=C\C(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)