AFD-21 maleate

AFD-21 maleate is a drug with antiarrhythmic activity. AFD-21 maleate inhibits sodium channels by binding to sodium channels in an inactive state, with both use-dependent and voltage-dependent effects. The unbinding rate of AFD-21 maleate is similar to that of Class I antiarrhythmic drugs with moderate kinetics. AFD-21 maleate can cause a slight prolongation of the action potential duration and significantly reduce the maximum rise rate of the action potential at certain concentrations. AFD-21 maleate also showed use-dependent blocking effects as stimulation frequency increased.

For research use only. We do not sell to patients.

  • CAS No.: 99465-44-8
  • Formula: C28H39NO5
  • Molecular Weight:469.61
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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