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Art. -Nr.: HY-185699A

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Antibacterial agent 350 TFA

Name: Antibacterial agent 350 TFA
Brand: MedChemExpress
SKU: HY-185699A
Price: 875.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Based on 1 Customer Validation

Antibacterial agent 350 TFA is a membrane stabilizer/disruptor with antibacterial activity. Antibacterial agent 350 TFA reduces glucose-induced efflux efficiency and slightly impairs outer membrane stability. Antibacterial agent 350 TFA significantly decreases the bacteriostatic MIC₅₀ of Ceftazidime (HY-B0593) or Ciprofloxacin (HY-B0356), but increases the MIC₅₀ of Amikacin (HY-B0509A). Antibacterial agent 350 TFA can be used for the research of Pseudomonas aeruginosa infections.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Reinheit: 96.06%
Formel: C₂₇H₅₁F₃N₄O₂
Molecular Weight:520.71

Speicherung:

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Antibacterial agent 350 TFA Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

Antibacterial agent 350 (compound 3) (15.6-125 μM; 60 min) TFA causes slight outer membrane permeabilization in Pseudomonas aeruginosa PA01, but its primary activity is potent efflux inhibition, which is significantly greater than its permeabilization effect at all tested concentrations^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

CHO-K1 Chinese Hamster Ovary cells
Concentration:

30-1200 μM
Incubation Time:

24 h
Result:

Had an IC₅₀ of 320.5 μM for CHO-K1 cells, which is significantly higher than the IC₅₀ of positive control doxorubicin (48.3 μM).

Chemical Information

Appearance Solid
Molecular Weight 520.71
Formel C₂₇H₅₁F₃N₄O₂
Color White to off-white
SMILES

NCCCNCCCCNCCCNC/C=C(C)/CC/C=C(C)/CC/C=C(C)/C.OC(C(F)(F)F)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
SDS (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Borselli D, et al. Polyamino-isoprenic derivatives block intrinsic resistance of P. aeruginosa to doxycycline and chloramphenicol in vitro[J]. PLoS One, 2016, 11(5): e0154490.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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