CD38 Antibody (YA540)

Cat. No.: HY-P80386: Data Sheet COA
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User Guide for Antibodies
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CD38 Antibody (YA540) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD38.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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CD38 Antibody (YA540) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
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Background
Documentation

Description

CD38 Antibody (YA540) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD38.

Host

Rabbit

Clonality

Recombinant, Monoclonal

Molecular Weight

Predicted band size: 34 kDa；

Observed band size: 45 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P28907

Gene ID

952 [NCBI]

Immunogen

Synthetic peptide corresponding to Human CD38.AA range:250-300.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50

Sensitivity	Endogenous	Purity	Protein A affinity purified.
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 1*PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Verification Image

Western blot analysis of extracts from Ramos using CD38 antibody. Proteins were transferred to a PVDF membrane and blocked with 5% nonfat powdered milk in PBST for 2 hour at room temperature. The primary antibody (1/1000) and loading control antibody (GAPDH, 1/3000) was diluted with 5% nonfat powdered milk in PBST at 4°C overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/8,000) was incubated for 45min at room temperature.

Background

Function：Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion (PubMed:7961800, PubMed:8253715). Synthesizes the Ca(2+) mobilizer nicotinate-adenine dinucleotide phosphate, NAADP(+), from 2'-phospho-cADPR and nicotinic acid, as well as from NADP(+) and nicotinic acid. At both pH 5.0 and pH 7.4 preferentially transforms 2'-phospho-cADPR into NAADP(+), while preferentially cleaving NADP(+) to cADPR and ADPRP rather than into NADDP(+) (PubMed:16690024). Has cADPR hydrolase activity (PubMed:7961800, PubMed:8253715)

Subcellular Localization：Cell surface; Membrane; Single-pass type II membrane protein

Expression：
Tissue_specificity:It is highly expressed in the pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma, and neuroblastoma.

Isoforms & Post-Translational Modification：P28907 has 2 isomers: P28907-1: 34328 Da (predicted); P28907-2: 13788 Da (predicted).

Subunit：Homodimer

RRID

AB_3102473

Database

Entrez Gene: 952 Human

SwissProt: P28907 Human

OMIM: 107270 Human

Research Field

Immunology

Documentation

Select Batch:

Data Sheet (235 KB) SDS (313 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

CD38 Antibody (YA540) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CD38 Antibody (YA540)

CD38 Antibody (YA540) Featured Recommendations:

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Background

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CD38 Antibody (YA540) Related Classifications

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