CD68 Antibody (YA798)

Cat. No.: HY-P80066: Data Sheet COA
SDS
User Guide for Antibodies
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Technical Support

CD68 Antibody (YA798) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD68.

For research use only. We do not sell to patients.

Size	Stock	Quantity
Free Sample	Apply now
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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CD68 Antibody (YA798) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
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Background
Documentation

Description

CD68 Antibody (YA798) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD68.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 37 kDa；

Observed band size: 75-130 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P34810

Gene ID

968 [NCBI]

Immunogen

Synthetic peptide corresponding to Human CD68.AA range:320-354.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:200
FC FC: Flow Cytometry	1:50-1:100

Sensitivity	Endogenous	Purity	Protein G affinity purified.
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in 1*PBS (pH7.4), 0.2% BSA and 50% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Verification Image

Western blot analysis of extracts from THP-1 (lane 1) and HepG2 (lane 2) and RAW264.7 (lane 3) using CD68 Antibody (YA798) antibody. Proteins were transferred to a PVDF membrane and blocked with 5% nonfat powdered milk in PBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (GAPDH, 1/3000) was diluted with 5% nonfat powdered milk in PBST at 4°C overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/8,000) was incubated for 45min at room temperature.

Background

Function：Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells

Subcellular Localization：Cell membrane; Single-pass type I membrane protein; Endosome membrane; Single-pass type I membrane protein; Lysosome membrane; Single-pass type I membrane protein

Expression：
Tissue_specificity:It is highly expressed in blood monocytes and tissue macrophages. It is also expressed in lymphocytes, fibroblasts, and endothelial cells. It is expressed in many tumor cell lines, which may enable them to attach to selectins on vascular endothelium, thereby promoting their spread to secondary sites.

Isoforms & Post-Translational Modification：P34810 has 3 isomers: P34810-1: 37408 Da (predicted); P34810-2: 31738 Da (predicted); P34810-3: 34654 Da (predicted).
N- and O-glycosylated

RRID

AB_3102065

Database

Entrez Gene: 968 Human

SwissProt: P34810 Human

OMIM: 153634 Human

Research Field

Immunology

Synonyms

CD 68 antibody; CD68 antibody; CD68 antigen antibody; CD68 molecule antibody; CD68_HUMAN antibody; DKFZp686M18236 antibody; gp11 antibody; Gp110 antibody; LAMP4 antibody; Macrophage antigen CD68 (microsialin) antibody; MACROPHAGE ANTIGEN CD68 antibody; Macrosialin antibody; SCARD1 antibody; Scavenger receptor class D member 1 antibody

Documentation

Select Batch:

Data Sheet (234 KB) SDS (315 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

CD68 Antibody (YA798) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CD68 Antibody (YA798)

CD68 Antibody (YA798) Featured Recommendations:

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CD68 Antibody (YA798) Related Classifications

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