2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Conjugated Primary Antibodies
  5. Histone H3 Antibody(HRP) (YA5336)

Histone H3 Antibody(HRP) (YA5336)

Cat. No.: HY-P85644
User Guide for Antibodies Technical Support

Histone H3 Antibody(HRP) (YA5336) is a mouse-derived and horseradish peroxidase (HRP) IgG monoclonal antibody, targeting to Histone H3.

For research use only. We do not sell to patients.

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

Histone H3 Antibody(HRP) (YA5336) is a mouse-derived and horseradish peroxidase (HRP) IgG monoclonal antibody, targeting to Histone H3.
Host

Mouse
Clonality

Monoclonal
Species Reactivity
Zebrafish
SwissProt ID
Gene ID
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:1000-3000
Purity affinity chromatography. Conjugation HRP
Modification Unmodified Isotype IgG
Appearance

Liquid
Formulation

Supplied in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：P68431: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
Q71DI3: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
P84243: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
Subcellular Localization：P68431: Nucleus; Chromosome
Q71DI3: Nucleus; Chromosome
P84243: Nucleus; Chromosome
Subunit：P68431: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
Q71DI3: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
P84243: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
Synonyms
HIST1H3A
Documentation
User Guide for Antibodies (1077 KB)

Histone H3 Antibody(HRP) (YA5336) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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