Histone H3 Antibody(HRP) (YA5336)
(Synonyms: HIST1H3A)Histone H3 Antibody(HRP) (YA5336) is a mouse-derived and horseradish peroxidase (HRP) IgG monoclonal antibody, targeting to Histone H3.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB
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Reactivity :
Zebrafish
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Formulation:
Supplied in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
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Conjugation:
HRP
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
|---|---|
| Dilution Ratio | 1:1000-3000 |
Product Details
Histone H3 Antibody(HRP) (YA5336) is a mouse-derived and horseradish peroxidase (HRP) IgG monoclonal antibody, targeting to Histone H3.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityZebrafish
affinity chromatography.
HRP
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Histone H3 is a P68431: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
Q71DI3: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
P84243: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling -
Subcellular Localization
P68431: Nucleus; Chromosome
Q71DI3: Nucleus; Chromosome
P84243: Nucleus; Chromosome -
Subunit
P68431: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
Q71DI3: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
P84243: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. -
Synonyms
HIST1H3A
Documentation
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