DL-Arginine-¹³C₆,¹⁵N₄ hydrochloride  (Synonyms: (±)-Arginine-13C6,15N4 hydrochloride)

DL-Arginine-¹³C₆,¹⁵N₄ hydrochloride is ¹³C and ¹⁵N-labeled DL-Arginine hydrochloride (HY-W014375). DL-Arginine ((±)-Arginine) hydrochloride is the racemic compound of L-Arginine (HY-N0455) and D-Arginine (HY-W016781). Arginine is an essential amino acid that requires additional supplementation in traumatic or diseased conditions. Arginine is involved in T cell activation, proliferation, and differentiation, and affects the function of immune cells^[1].

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

220.59

¹³C₆H₁₅Cl¹⁵N₄O₂

220144-84-3

Solid

White to off-white

[15NH2][13CH]([13C](O)=O)[13CH2][13CH2][13CH2][15NH][13C]([15NH2])=[15NH].Cl

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. Tovaglieri A. Development of a Human Primary Intestine Chip and Identification of Species-Specific Microbiome Metabolites Enhancing Enterohemorrhagic E. Coli Pathogenesis[D]. ETH Zurich, 2019.