21-Deoxycortisol-d8
Based on 1 Customer Validation
21-Deoxycortisol-d8 is the d8-labeled 21-Deoxycortisol (HY-113405). 21-Deoxycortisol is an adrenal-specific C21 steroid that accumulates via alternative pathways due to 21-hydroxylase (CYP21A2/P450c21) deficiency. 21-Deoxycortisol serves as a sensitive and specific biomarker for steroid 21-hydroxylase deficiency (21OHD).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98.79%
- CAS. Nr.: 2479914-04-8
- Formel: C21H22D8O4
- Molecular Weight:354.51
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Help & FAQs
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Biologische Aktivität
Beschreibung
Anwendung
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 2479914-04-8
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Unlabeled CAS 641-77-0
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Appearance Solid
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Molecular Weight 354.51
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Formel C21H22D8O4
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Color White to off-white
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SMILES
C[C@@]12[C@](CC[C@]2(O)C(C([2H])([2H])[2H])=O)([H])[C@@]3([H])[C@@]([C@H](C1)O)([H])[C@@]4(C(C([2H])([2H])C3)=C([2H])C(C([2H])([2H])C4)=O)C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Reinheit & Dokumentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Franks RC. Plasma 17-hydroxyprogesterone, 21-deoxycortisol and cortisol in congenital adrenal hyperplasia. J Clin Endocrinol Metab. 1974;39(6):1099-1102. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
21-Deoxycortisol-d8 Related Classifications
HY-113405S1 Related Classifications
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Keywords
- 21-Deoxycortisol-d8
- 2479914-04-8
- Isotope-Labeled Compounds
- Endogenous Metabolite
- steroid 21-hydroxylase deficiency
- nonclassic congenital adrenal hyperplasia
- congenital adrenal hyperplasia
- adrenal steroid
- CYP21A2 heterozygosity
- 11β-hydroxylase
- hyperandrogenic females
- 17-hydroxyprogesterone
- polycystic ovary syndrome
- premature infants
- Inhibitor
- inhibitor
- inhibit