SL910102
SL910102 is a nonpeptide angiotensin AT1 receptor antagonist.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 144756-71-8
- Formel: C30H30N6O
- Molecular Weight:490.60
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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AT1 Receptor |
SL910102 (SL 91.0102-90 DL) is a unlabelled nonpeptide AT1-antagonist, which is tested for its ability to compete with [125J](Sar1-Ile8)-angiotensin II for specific AT1-receptor sites in rat lung homogenate[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 144756-71-8
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Molecular Weight 490.60
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Formel C30H30N6O
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SMILES
O=C1N=C(CCC2=CC=CC=C2)NC(CCCC)=C1CC3=CC=C(C4=CC=CC=C4C5=NN=NN5)C=C3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
For saturation as well as displacement studies, rat lung homogenate is incubated in either Hepes-buffer or blank human or rat plasma yielding 50 μg protein per well in a total assay volume of 300 μL. To ensure equilibrium conditions (see binding kinetics), the samples are maintained for 60 min at 25°C under continuous rotation. All experiments are carried out in duplicate, and the results are confirmed with n=3-5 replicates over the following days[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
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