AD06
AD06 is a SARS-CoV-2 main protease (Mpro) inhibitor with an IC50 of 163.3 nM. AD06 undergoes nucleophilic attack by deprotonated Cys145, thereby blocking viral replication. AD06 inhibits the activity of wild-type SARS-CoV-2 and shows no significant cytotoxicity in mammalian cells. AD06 can be used in studies related to SARS-CoV-2 infection.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C22H32ClN5O5S
- Molecular Weight:514.04
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
AD06 exhibits moderate antiviral activity against SARS-CoV-2 in Vero E6 cells with an EC50 of 25.58 μM[1].
AD06 does not exhibit notable cytotoxicity in Vero E6 cells, with a CC50 > 100 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Molecular Weight 514.04
-
Formel C22H32ClN5O5S
-
SMILES
CC(C[C@@H](C(N[C@@H](C[C@@H]1CCNC1=O)C=O)=O)NC([C@H](C(C)C)NC(C2=CSC(Cl)=N2)=O)=O)C
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
AD06 Related Classifications
HY-184147 Related Classifications
Powered by Bioz