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Art. -Nr.: HY-119925

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Amaralin

Amaralin is a sesquiterpene lactone with analgesic activity, which exists in the leaves and stems of Helenium amarum (Raf.) H. Rock. When administered subcutaneously, Amaralin produces analgesic effects in the mouse tail-flick test. When administered subcutaneously, Amaralin inhibits acetic acid-induced writhing syndrome in mice. Amaralin can be used for pain-related research.

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CAS. Nr.: 6831-10-3
Formel: C₁₅H₂₀O₄
Molecular Weight:264.32

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Amaralin Chemical Structure

CAS. Nr.: 6831-10-3

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Biologische Aktivität
- Beschreibung
- In Vitro
- In Vivo
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

Amaralin (compound Ia) is a pseudoguaianolide sesquiterpene lactone. It readily forms monoacetate at room temperature^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Amaralin (compound Ia) (10-25 mg/kg; s.c.) produces potent analgesic effects in mouse tail flick test and inhibits acetic acid-induced writhing syndrome in mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 6831-10-3
Molecular Weight 264.32
Formel C₁₅H₂₀O₄
SMILES

C[C@]12[C@@]([C@@]3([C@]([C@@H]1O)(O3)[H])[H])([C@H](C)C[C@]4([C@](C2)(C(=C)C(=O)O4)[H])[H])[H]
Structure Classification
- Terpenoids
- Sesquiterpenes
Initial Source
- Plants
- Compositae
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Lucas R A, et al. A New Sesquiterpene Lactone with Analgesic Activity from Helenium amarum (Raf.) H. Rock. The Journal of Organic Chemistry, 1964, 29(6): 1549-1554.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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