DAPL1 - death associated protein like 1 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 92196

About DAPL1

This gene has 4 transcripts (splice variants), 165 orthologues and 1 paralogue. Biased expression in esophagus (RPKM 59.4), skin (RPKM 46.5) and 3 other tissues.

Summary

Predicted to enable death domain binding activity. Predicted to be involved in apoptotic signaling pathway; cellular response to amino acid starvation; and negative regulation of Autophagy. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

DAPL1 Products (1)

mRNA Protein Name
NM_001017920.3 NP_001017920.2 death-associated protein-like 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DAPL1 Protein Structure

DAP

DAP: Death-associated protein (13 - 106)

  • 0
  • 100
  • 107 a.a.
Protein Preferred Names Protein Names

death-associated protein-like 1

  • early epithelial differentiation-associated protein

DAPL1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
DAPL1 A0PJW8 FNDC3B Homo sapiens Q53EP0-3
Validated Y2H
32296183
Intra
DAPL1 A0PJW8 ZIC1 Homo sapiens Q15915
Validated Y2H
32296183
Intra
DAPL1 A0PJW8 LSM1 Homo sapiens O15116
Validated Y2H
32296183
Intra
DAPL1 A0PJW8 FHL2 Homo sapiens Q14192
Validated Y2H
32296183
Intra
DAPL1 A0PJW8 TSR2 Homo sapiens Q969E8
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS03530 DAPL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris DAPL1 VGNC VGNC:39772
Bos taurus DAPL1 VGNC VGNC:27879
Rattus norvegicus DAPL1 RGD RGD:1309610
Mus musculus DAPL1 MGD MGI:1923997
Felis catus DAPL1 VGNC VGNC:61339
Others DAPL1 NCBI