Norchelerythrine
Norchelerythrine is an alkaloid isolated from the roots of Zanthoxylum capense with antibacterial activity against gram-positive and gram-negative bacteria. Norchelerythrine exhibits inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecalis and Escherichia coli with MIC values >50 µg/mL.
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- CAS. Nr.: 6900-99-8
- Formel: C20H15NO4
- Molecular Weight:333.34
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
MIC: >50 µg/mL (Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecalis and Escherichia coli)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
>10 μM
Compound: 3a
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Antiproliferative activity against human HCT116 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HCT116 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
|
[PMID: 26026362] |
| HL-60 | IC50 |
>10 μM
Compound: 3a
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Antiproliferative activity against human HL60 cells assessed as inhibition of cell viability after 48 hrs by WST-1 assay
Antiproliferative activity against human HL60 cells assessed as inhibition of cell viability after 48 hrs by WST-1 assay
|
[PMID: 26026362] |
Chemical Information
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CAS. Nr. 6900-99-8
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Molecular Weight 333.34
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Formel C20H15NO4
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SMILES
COC1=C(OC)C2=CN=C3C(C(C=CC3=C2C=C1)=C4)=CC5=C4OCO5
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)