Art. -Nr.: HY-108299

Perfluamine

Name: Perfluamine
Brand: MedChemExpress
SKU: HY-108299
Price: 25.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: Perfluorotripropylamine; FTPA; Tris(perfluoropropyl)amine)

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Perfluamine (Perfluorotripropylamine; FTPA; Tris (perfluoropropyl) amine) is a colorless, odorless, inert liquid with high gas-dissolving capacity. Perfluamine is non-toxic in rats, forms stable emulsions, is slowly eliminated from organs, and dissolves and transports oxygen. Perfluamine can be used to prepare oil-in-water emulsions as oxygen-carrying media. Perfluamine can be used in organic synthesis-related research, such as encapsulation in PLGA-PEG nanocarriers to obtain PLGA-PEG/FC-3283 emulsions.

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Reinheit : 98.0%
CAS. Nr.: 338-83-0
Formel: C₉F₂₁N
Molecular Weight:521.07

Speicherung:

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Perfluamine Chemical Structure

CAS. Nr.: 338-83-0

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Lösungsmittel & Löslichkeit
- In Vitro
- In Vivo
Reinheit & Dokumentation
Verweise
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

Perfluamine (FTPA) was classified as forming a favorable perfluorocarbon emulsion with Pluronic F-68 and egg yolk phospholipids in a cell-free emulsion stability assay^[1].
Perfluamine was encapsulated in PLGA‑PEG copolymer to prepare PLGA‑PEG/FC‑3283 emulsion; this emulsion exhibited low cytotoxicity toward HCT116 cells and significantly enhanced cell viability after hypoxic injury in a hypoxia‑reoxygenation cell model^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS. Nr. 338-83-0
Appearance Liquid (Density: 1.822 g/cm³)
Molecular Weight 521.07
Formel C₉F₂₁N
Color Colorless to light yellow
SMILES

FC(F)(F)C(F)(F)C(N(C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)F)(F)F
Synonyms

Perfluorotripropylamine; FTPA; Tris(perfluoropropyl)amine
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 100 mg/mL (191.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

1.9191 mL

9.5956 mL

19.1913 mL

5 mM

0.3838 mL

1.9191 mL

3.8383 mL

10 mM

0.1919 mL

0.9596 mL

1.9191 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

Stock Solution Working Solution

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline

Solubility: ≥ 2.5 mg/mL (4.80 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)

Solubility: ≥ 2.5 mg/mL (4.80 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil

Solubility: ≥ 2.5 mg/mL (4.80 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage Dosage
mg/kg
Animal Weight (Per Animal) Animal Weight (Per Animal)
g
Dosing Volume (Per Animal) Dosing Volume (Per Animal)
μL
Number of Animals Number of Animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

%
DMSO +

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
%
+
+
%
Tween-80 + +
%
Saline +

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Working solution concentration: 0.22 mg/mL

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (277 KB)
SDS (615 KB)
- English - EN (615 KB)
- Français - FR (615 KB)
- Deutsch - DE (615 KB)
- Norwegian - NO (615 KB)
- Español - ES (615 KB)
- Swedish - SV (615 KB)
- Italian - IT (615 KB)
- Korean - KR (615 KB)
- Portuguese - PT (615 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Yokoyama K, et al. A perfluorochemical emulsion as an oxygen carrier. Artificial Organs. 1984 Feb;8(1):34-40.

[2]. Wen Z, et al. Preparation of Perfluorocarbon Emul-sion and Its Application in Cells Re-oxygenation. General Chemistry. 2016 Mar 31;2(1):38.

[3]. Teicher BA, et al. A new concentrated perfluorochemical emulsion and carbogen breathing as an adjuvant to treatment with antitumor alkylating agents. Journal of cancer research and clinical oncology. 1992;118(7):509-14.

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	1.9191 mL	9.5956 mL	19.1913 mL	47.9782 mL
	5 mM	0.3838 mL	1.9191 mL	3.8383 mL	9.5956 mL
	10 mM	0.1919 mL	0.9596 mL	1.9191 mL	4.7978 mL
	15 mM	0.1279 mL	0.6397 mL	1.2794 mL	3.1985 mL
	20 mM	0.0960 mL	0.4798 mL	0.9596 mL	2.3989 mL
	25 mM	0.0768 mL	0.3838 mL	0.7677 mL	1.9191 mL
	30 mM	0.0640 mL	0.3199 mL	0.6397 mL	1.5993 mL
	40 mM	0.0480 mL	0.2399 mL	0.4798 mL	1.1995 mL
	50 mM	0.0384 mL	0.1919 mL	0.3838 mL	0.9596 mL
	60 mM	0.0320 mL	0.1599 mL	0.3199 mL	0.7996 mL
	80 mM	0.0240 mL	0.1199 mL	0.2399 mL	0.5997 mL
	100 mM	0.0192 mL	0.0960 mL	0.1919 mL	0.4798 mL

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Perfluamine