PSB-24000
PSB-24000 (Compound 27) is a selective ecto-5'-nucleotidase (CD73) inhibitor with a Ki value of 563 nM against human CD73 (Ki= 481 nM at membrane-bound CD73 in triple-negative breast cancer cells). PSB-24000 interferes with CD73's recognition and action on the substrate AMP, and prevents the generation of immunosuppressive and cancer-promoting adenosine from AMP. PSB-24000 is promising for research of cancers.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C20H28ClN5O6P2
- Molecular Weight:531.87
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
Chemical Information
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Molecular Weight 531.87
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Formel C20H28ClN5O6P2
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SMILES
O=P(CP(O)(O)=O)(OCCCCCCN1C=NC2=C(N(CC3=CC=CC=C3)C)N=C(Cl)N=C12)O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
PSB-24000 Related Classifications
HY-172801 Related Classifications
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