QPy-TPA
QPy-TPA is a lipopjilc probes, which induces non-ferroptotic cell death and lipid dynamic regularion in B16 and HepG2 cells upon light irradiation. QPy-TPA reveals a maximum absorption wavelength of 400 nm and a maximum emission wavelength of 590 nm.
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- CAS. Nr.: 2738332-94-8
- Formel: C33H24N4O
- Molecular Weight:492.57
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Beschreibung
In Vitro
QPy-TPA (5 μM) exhibits photocytotoxicity in cells B16 and HepG2, while QPy-TPA (50 μM) reveals a survival rate >50% without light irradiation[1].
QPy-TPA upregulates oxidized lipids upon light irradiation, especially PCs and PEs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:B16, HepG2
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Concentration:0-50 μM
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Incubation Time:48 h
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Result:Exhibited survival rate >50% without light irradiation, decreased cell viabilities in B16 and HepG2 upon light irradiation, which is irreversible by Fer-1.
Chemical Information
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CAS. Nr. 2738332-94-8
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Molecular Weight 492.57
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Formel C33H24N4O
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SMILES
O=C1C2=CC=CC=C2NC(C3=CC(/C=C/C(C=C4)=CC=C4N(C5=CC=CC=C5)C6=CC=CC=C6)=CC=N3)=N1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
QPy-TPA Related Classifications
HY-163287 Related Classifications
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