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Art. -Nr.: HY-167824

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SSR180711

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SSR180711 is a potent and subtype-selective α7 agonist with activity in Alzheimer's disease and schizophrenia research. SSR180711 can be used to study subtypes of intracerebral hemorrhage associated with cerebral small vessel disease. SSR180711 shows potential in electrophysiological and behavioral studies to evaluate its effects on cognitive function. SSR180711 also has potential for studying cerebrovascular lesions and their effects.

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Reinheit: 99.52%
CAS. Nr.: 298198-52-4
Formel: C₁₄H₁₇BrN₂O₂
Molecular Weight:325.20

Speicherung:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

SSR180711 Chemical Structure

CAS. Nr.: 298198-52-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Alle Endogenous Metabolite Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
GH4-C1	EC₅₀	0.9 μM Compound: 29, SSR180711	Partial agonist activity at human alpha7 nAChR expressed in GH4C1 cells relative to acetylcholine Partial agonist activity at human alpha7 nAChR expressed in GH4C1 cells relative to acetylcholine	[PMID: 21919481]
HEK293	IC₅₀	>3160 nM Compound: 5	Displacement of [3H]LY278584 from human 5HT3 receptor expressed in HEK293 cells Displacement of [3H]LY278584 from human 5HT3 receptor expressed in HEK293 cells	[PMID: 19576766]
IMR-32	IC₅₀	>6480 nM Compound: 5	Displacement of [3H]epibatidine from alpha3 nAChR in human IMR32 cells Displacement of [3H]epibatidine from alpha3 nAChR in human IMR32 cells	[PMID: 19576766]
Oocyte	EC₅₀	4.4 μM Compound: 29, SSR180711	Partial agonist activity at human alpha7 nAChR expressed in Xenopus oocytes relative to acetylcholine Partial agonist activity at human alpha7 nAChR expressed in Xenopus oocytes relative to acetylcholine	[PMID: 21919481]

Chemical Information

CAS. Nr. 298198-52-4
Appearance Solid
Molecular Weight 325.20
Formel C₁₄H₁₇BrN₂O₂
Color Off-white to light brown
SMILES

O=C(N1CCN2CCC1CC2)OC3=CC=C(C=C3)Br
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
SDS (644 KB)
- English - EN (644 KB)
- Français - FR (644 KB)
- Deutsch - DE (644 KB)
- Norwegian - NO (644 KB)
- Español - ES (644 KB)
- Swedish - SV (644 KB)
- Italian - IT (644 KB)
- Korean - KR (644 KB)
- Portuguese - PT (644 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. CADMUS: A Novel MRI-Based Classification of Spontaneous Intracerebral Hemorrhage Associated With Cerebral Small Vessel Disease [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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SSR180711

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SSR180711 Related Classifications

HY-167824 Related Classifications