STING18
Based on 1 Customer Validation
STING18 (Stimulator of interferon genes 18) is a compound that inhibits STING protein by utilizing a small molecule active site dimer, with good oral exposure, slow binding kinetics, and functional inhibitory activity on STING-mediated cytokine release.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.6%
- CAS. Nr.: 2706536-26-5
- Formel: C29H27ClFNO5
- Molecular Weight:523.98
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biologische Aktivität
Chemical Information
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CAS. Nr. 2706536-26-5
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Appearance Solid
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Molecular Weight 523.98
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Formel C29H27ClFNO5
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Color White to off-white
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SMILES
O=C(CC1C2=CC=C(C=C2C(N(C1C3=CC=C4OCCOC4=C3)C5=CC=C(C(C)(C)C)C(Cl)=C5)=O)F)O
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Synonyms
Stimulator of interferon genes 18
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMF : 10 mg/mL (19.08 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMF | 1 mM | 1.9085 mL | 9.5423 mL | 19.0847 mL | 47.7117 mL |
| 5 mM | 0.3817 mL | 1.9085 mL | 3.8169 mL | 9.5423 mL | |
| 10 mM | 0.1908 mL | 0.9542 mL | 1.9085 mL | 4.7712 mL | |
| 15 mM | 0.1272 mL | 0.6362 mL | 1.2723 mL | 3.1808 mL |