Syringolin A
Syringolin A is a plant elicitor that can be produced by the plant pathogen Pseudomonas syringae pv. syringae. Syringolin A exhibits anti-proliferative activity against a variety of cancer cells (IC50 for SK-N-SH, LAN-1, SKOV3 is 20-25 µM), induces apoptosis in SK-N-SH through upregulation of p53 expression and downregulation of Akt/PKB proteins.
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- CAS. Nr.: 212115-96-3
- Formel: C24H39N5O6
- Molecular Weight:493.60
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MM1.S | IC50 |
8.5 μM
Compound: 1
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Cytotoxicity against human MM1.S cells
Cytotoxicity against human MM1.S cells
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[PMID: 38704960] |
| MM1.S | IC50 |
8500 nM
Compound: 1
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Cytotoxicity against human MM1S cells
Cytotoxicity against human MM1S cells
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[PMID: 26231162] |
Chemical Information
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CAS. Nr. 212115-96-3
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Molecular Weight 493.60
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Formel C24H39N5O6
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SMILES
CC(C)[C@@H](C(O)=O)NC(N[C@H](C(N[C@@H]1C(N[C@@H](C(C)C)/C=C/C(NCC/C=C/1)=O)=O)=O)C(C)C)=O
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Structure Classification
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Initial Source
Pseudomonas syringae pv.
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Syringolin A Related Classifications
HY-N15314 Related Classifications
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