WGU55
WGU55 is a selective and potent reversible type II transmembrane serine protease TMPRSS6 inhibitor with a Ki of 12.15 nM. WGU55 inhibits TMPRSS6 activity with an IC50 of 138 nMin KEK293 cells. WGU55 has a Ki of 3510 nM (SI = 289) against the homologous protease matriptase and a Ki of 5.2 μM against the coagulation key protease Factor Xa. WGU55 can be used for the research of iron overload related diseases, such as hereditary hemochromatosis.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C41H43N7O6S
- Molecular Weight:761.89
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
Chemical Information
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Molecular Weight 761.89
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Formel C41H43N7O6S
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SMILES
O=C(CCC1=CC=CC=C1)N[C@H](C(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(C2=NC(C=CC=C3)=C3S2)=O)=O)=O)CC4=CC=C(C5=CC=CC=C5)C=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
WGU55 Related Classifications
HY-180217 Related Classifications
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