ZCL279
Based on 1 publication(s) in Google Scholar
ZCL279 is a small molecule modulator (SMM) that inhibits Cdc42-intersectin (ITSN) interaction. ZCL279 can activate Cdc42 (a cytoplasmic small GTPase in the Ras superfamily) at lower concentrations (<10 μM) and significantly inhibit it at higher concentrations (<10 μM).
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- Reinheit: 99.20%
- CAS. Nr.: 664975-73-9
- Formel: C24H18N2O7S2
- Molecular Weight:510.54
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) ZCL279
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Biologische Aktivität
Chemical Information
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CAS. Nr. 664975-73-9
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Appearance Solid
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Molecular Weight 510.54
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Formel C24H18N2O7S2
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Color White to off-white
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SMILES
OC1=CC=CC=C1NS(=O)(C2=CC=C(OC3=C4C=C(S(=O)(NC5=C(O)C=CC=C5)=O)C=C3)C4=C2)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Rejuvenation Res
Resveratrol Inhibits Pancreatic Cancer Progression by Regulating CDC42 Succinylation and Disrupting the Extracellular Matrix. [Abstract]2025 Sep 18. PMID: 40965218
Lösungsmittel & Löslichkeit
DMSO : 50 mg/mL (97.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (276 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9587 mL | 9.7936 mL | 19.5871 mL | 48.9678 mL |
| 5 mM | 0.3917 mL | 1.9587 mL | 3.9174 mL | 9.7936 mL | |
| 10 mM | 0.1959 mL | 0.9794 mL | 1.9587 mL | 4.8968 mL | |
| 15 mM | 0.1306 mL | 0.6529 mL | 1.3058 mL | 3.2645 mL | |
| 20 mM | 0.0979 mL | 0.4897 mL | 0.9794 mL | 2.4484 mL | |
| 25 mM | 0.0783 mL | 0.3917 mL | 0.7835 mL | 1.9587 mL | |
| 30 mM | 0.0653 mL | 0.3265 mL | 0.6529 mL | 1.6323 mL | |
| 40 mM | 0.0490 mL | 0.2448 mL | 0.4897 mL | 1.2242 mL | |
| 50 mM | 0.0392 mL | 0.1959 mL | 0.3917 mL | 0.9794 mL | |
| 60 mM | 0.0326 mL | 0.1632 mL | 0.3265 mL | 0.8161 mL | |
| 80 mM | 0.0245 mL | 0.1224 mL | 0.2448 mL | 0.6121 mL |