PSB-18422
PSB-18422 is a GPR17 agonist, with an EC50 of 0.0279 μM for humans, 0.47 μM for rats, 0.753 μM for mice, and a human Ki of 1.46 μM. PSB-18422 triggers intracellular calcium mobilization via cross-species activation of GPR17. PSB-18422 can be used in the research of allergic bronchial inflammation.
For research use only. We do not sell to patients.
- CAS No.: 2244978-64-9
- Formula: C12H9BrFNO4
- Molecular Weight:330.11
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
PSB-18422 (Compound 33) potently activates human GPR17 in 1321N1 astrocytoma cells, with an EC50 of 0.0279 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2244978-64-9
-
Molecular Weight 330.11
-
Formula C12H9BrFNO4
-
SMILES
O=C(C1=C(CCC(O)=O)C2=C(C=C(C=C2F)Br)N1)O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PSB-18422 Related Classifications
HY-182724 Related Classifications
Powered by Bioz