Tedixaban
Tedixaban (Tedixabanum) is a Factor Xa inhibitor and anticoagulant with an IC50 of 0.50 nM. Tedixaban is applicable to research on thrombosis-related complications.
For research use only. We do not sell to patients.
- CAS No.: 1333126-80-9
- Formula: C23H22ClN5O2
- Molecular Weight:435.91
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Tedixaban (DD217) is a small-molecule compound belonging to the class of coagulation factor Xa inhibitors. It has an in vitro IC50 of 0.50 nM, exhibits tight-binding characteristics, and acts as a competitive binding ligand, with an MM/GBSA total binding free energy of -46.9 kcal/mol[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 1333126-80-9
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Molecular Weight 435.91
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Formula C23H22ClN5O2
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SMILES
O=C(C1=CC=C(N(C)C(C)=N)C=C1)NC2=CC=C(C)C=C2C(NC3=NC=C(C=C3)Cl)=O
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Synonyms
Tedixabanum
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tedixaban Related Classifications
HY-184102 Related Classifications
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