ATG5 PPI-IN-1
ATG5 PPI-IN-1 is a ATG5 protein-protein interaction inhibitor, with an IC50 of 27.43 μM for the ATG5-ATG16L1 interaction and an IC50 of 14.88 μM for the ATG5-TECAIR interaction.
For research use only. We do not sell to patients.
- CAS No.: 2841473-89-8
- Formula: C31H23NO5
- Molecular Weight:489.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
ATG5 PPI-IN-1 (Compound 17b) inhibits the ATG5-ATG16L1 interaction with an IC50 of 27.43 μM and the ATG5-TECAIR interaction with an IC50 of 14.88 μM in an in vitro HTRF binding assay[1].
ATG5 PPI-IN-1 does not have a quantifiable effect on autophagy incidence in COS-7 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2841473-89-8
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Molecular Weight 489.52
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Formula C31H23NO5
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SMILES
CC(C1=CC=CC(C2=CC=C(O2)/C=C(C3=O)\C=C(C4=CC=CC=C4)N3CC5=CC=C(C=C5)C(O)=O)=C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ATG5 PPI-IN-1 Related Classifications
HY-183731 Related Classifications
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