ATG5 PPI-IN-1
ATG5 PPI-IN-1 is a ATG5 protein-protein interaction inhibitor, with an IC50 of 27.43 μM for the ATG5-ATG16L1 interaction and an IC50 of 14.88 μM for the ATG5-TECAIR interaction.
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- No. CAS: 2841473-89-8
- Fòrmula: C31H23NO5
- Peso molecular:489.52
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
ATG5 PPI-IN-1 (Compound 17b) inhibits the ATG5-ATG16L1 interaction with an IC50 of 27.43 μM and the ATG5-TECAIR interaction with an IC50 of 14.88 μM in an in vitro HTRF binding assay[1].
ATG5 PPI-IN-1 does not have a quantifiable effect on autophagy incidence in COS-7 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2841473-89-8
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Peso molecular 489.52
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Fòrmula C31H23NO5
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SMILES
CC(C1=CC=CC(C2=CC=C(O2)/C=C(C3=O)\C=C(C4=CC=CC=C4)N3CC5=CC=C(C=C5)C(O)=O)=C1)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)