ATG5/TECAIR-IN-4
ATG5/TECAIR-IN-4 is an ATG5-targeting autophagy inhibitor. ATG5/TECAIR-IN-4 exhibits weak autophagy inhibitory activity. ATG5/TECAIR-IN-4 could be used in cancer-related research.
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- CAS 番号: 2841473-98-9
- 分子式: C30H23NO6S
- 分子量:525.57
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
ATG5/TECAIR-IN-4 (Compound 17i) shows no obvious inhibitory activity against ATG5-ATG16L1 protein-protein interactions[1].
ATG5/TECAIR-IN-4 shows weak inhibitory activity against ATG5-TECAIR protein-protein interactions, with IC50 values above 33 μM for interactions[1].
ATG5/TECAIR-IN-4 (20 μM; 6 h) does not effectively inhibit autophagy in COS-7 cells, with an autophagy incidence of 53.72%[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:COS-7 cells
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Concentration:20 μM
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Incubation Time:6 h
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Result:Resulted in an autophagy incidence of 53.72% in COS-7 cells.
化学情報
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CAS 番号 2841473-98-9
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分子量 525.57
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分子式 C30H23NO6S
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SMILES
CS(C(C=C1)=CC=C1C2=CC=C(O2)/C=C(C3=O)\C=C(C4=CC=CC=C4)N3CC5=CC=C(C=C5)C(O)=O)(=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)