2. ATG5-TECAIR-IN-3

ATG5-TECAIR-IN-3 is an ATG5-targeting autophagy inhibitor. ATG5-TECAIR-IN-3 exhibits weak autophagy inhibitory activity. ATG5-TECAIR-IN-3 could be used in cancer-related research.

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ATG5-TECAIR-IN-3

ATG5-TECAIR-IN-3 Chemical Structure

CAS No. : 2841473-98-9

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ATG5-TECAIR-IN-3 Related Antibodies

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Description

ATG5-TECAIR-IN-3 is an ATG5-targeting autophagy inhibitor. ATG5-TECAIR-IN-3 exhibits weak autophagy inhibitory activity. ATG5-TECAIR-IN-3 could be used in cancer-related research[1].

In Vitro

ATG5-TECAIR-IN-3 (Compound 17i) shows no obvious inhibitory activity against ATG5-ATG16L1 protein-protein interactions[1].
ATG5-TECAIR-IN-3 shows weak inhibitory activity against ATG5-TECAIR protein-protein interactions, with IC50 values above 33 μM for interactions[1].
ATG5-TECAIR-IN-3 (20 μM; 6 h) does not effectively inhibit autophagy in COS-7 cells, with an autophagy incidence of 53.72%[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ATG5-TECAIR-IN-3 Related Antibodies

Cell Autophagy Assay[1]

Cell Line: COS-7 cells
Concentration: 20 μM
Incubation Time: 6 h
Result: Resulted in an autophagy incidence of 53.72% in COS-7 cells.
Molecular Weight

525.57

Formula

C30H23NO6S
CAS No.
SMILES

CS(C(C=C1)=CC=C1C2=CC=C(O2)/C=C(C3=O)\C=C(C4=CC=CC=C4)N3CC5=CC=C(C=C5)C(O)=O)(=O)=O
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Purity & Documentation
References
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ATG5-TECAIR-IN-3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ATG5-TECAIR-IN-32841473-98-9TECAIRATG5mammalian cellsautophagy inhibitorCOS-7 cellsATG16L1Inhibitorinhibitorinhibit

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